609355-99-9Relevant academic research and scientific papers
Design, synthesis, and evaluation of novel biarylpyrimidines: A new class of ligand for unusual nucleic acid structures
Wheelhouse, Richard T.,Jennings, Sharon A.,Phillips, Victoria A.,Pletsas, Dimitrios,Murphy, Peter M.,Garbett, Nichola C.,Chaires, Jonathan B.,Jenkins, Terence C.
, p. 5187 - 5198 (2008/04/18)
Biarylpyrimidines are characterized as selective ligands for higher-order nucleic acid structures. A concise and efficient synthesis has been devised incorporating Suzuki biaryl cross-coupling of dihalopyrimidines. Two ligand series are described based on
Biarylpyrimidines: a new class of ligand for high-order DNA recognition.
Murphy, Peter M,Phillips, Victoria A,Jennings, Sharon A,Garbett, Nichola C,Chaires, Jonathan B,Jenkins, Terence C,Wheelhouse, Richard T
, p. 1160 - 1161 (2007/10/03)
Biarylpyrimidines bearing omega-aminoalkyl substituents have been designed as ligands for high-order DNA structures: spectrophotometric, thermal and competition equilibrium dialysis assays showed that changing the functional group for substituent attachme
