60956-25-4

Basic information

• Product Name: 2-BroMo-1,3-diMethyl-4-nitrobenzene
• Synonyms: 2-BroMo-1,3-diMethyl-4-nitrobenzene
• CAS NO: 60956-25-4
• Molecular Formula: C₈H₈BrNO₂
• Molecular Weight: 230.05862
• EINECS: -0
• Mol File: 60956-25-4.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-BroMo-1,3-diMethyl-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-1,3-diMethyl-4-nitrobenzene(60956-25-4)
• EPA Substance Registry System: 2-BroMo-1,3-diMethyl-4-nitrobenzene(60956-25-4)

Safety Data

• Hazardous Substances Data: 60956-25-4(Hazardous Substances Data)

Usage

General Description

2-Bromo-1,3-dimethyl-4-nitrobenzene is a synthetic, organic chemical compound characterized by the presence of bromine, nitro, and methyl groups attached to a benzene ring. The three functional groups - bromo, methyl and nitro - are positioned at the 2nd, 1st and 3rd, and 4th carbon atoms of the benzene ring, respectively. It presents as an aromatic compound due to the presence of the benzene ring and is likely to be used in various industrial applications including synthesis of other complex organic compounds, pharmaceuticals, and dyes. Exact properties such as melting point, boiling point, or toxicity can vary depending on conditions and are best determined empirically. It should be managed carefully due to potential risks associated with bromine and nitro groups.

Upstream product

• 576-22-7 2-Bromo-m-xylene 
• 67083-28-7 2,6-dimethyl-3-nitroaniline 

Downstream Products

• 66314-77-0 3-bromo-dimethylaniline 
• 69383-60-4 5-bromo-2,4-dimethylaniline 
• 693286-67-8 5-methylindole-4-boronic acid 
• 1063613-39-7 [2-(2-bromo-3-methyl-6-nitro-phenyl)-vinyl]-dimethyl-amine 
• 1449580-84-0 2-(5-methyl-1H-indol-4-yl)-5-[4-(3,3-dimethylpiperazin-1-yl)phenyl]-1,3-oxazole-4-carboxylic acid amide 
• 610794-15-5 4-bromo-5-methyl-1H-indole 
• 926922-44-3 6-methyl-2-N,N-dimethylaminomethyl-3-nitro-bromobenzene 
• 66314-79-2 3'-Brom-2,2-dichloro-2',4'-dimethylbenzoylacetanilid 
• 66314-78-1 3'-Brom-2',4'-dimethylbenzoylacetanilid 

Relevant articles and documents

AURORA AND FLT3 KINASES MODULATORS

The invention provides a compound having the formula (1): and salts thereof; wherein: R1 is hydrogen or C1-2 alkyl; and R2, R3 and R4 are the same or different and each is selected from hydrogen, C1-2 alkyl, fluorine, chlorine, C1-2 alkoxy and trifluoromethyl, provided that no more than two of R2, R3 and R4 are other than hydrogen. Also provided are pharmaceutical compositions containing the compounds and their use in medicine, and in particular in the treatment of cancer.

AURORA AND FLT3 KINASES MODULATORS

The invention provides a compound having the formula (1) useful as modulator of the activity of Aurora kinases and FLT3 kinases: and salts thereof; wherein: R1 is hydrogen or C1-2 alkyl; and R2, R3 and R4 are the same or different and each is selected from hydrogen, C1-2 alkyl, fluorine, chlorine, C1-2 alkoxy and trifluoromethyl, provided that no more than two of R2, R3 and R4 are other than hydrogen. Also provided are pharmaceutical compositions containing the compounds and their use in medicine, and in particular in the treatment of cancer

INDOL-4-YL-PYRIMIDINYL-2-YL-AMINE DERIVATIVES AND USE THEREOF AS CYCLIN DEPENDANT KINASE INHIBITORS

The present application, describes organic compounds of formula I that are useful for the treatment, prevention and/or amelioration of cyclin dependent limase mediated diseases. (I)