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4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[(1-methyl-4-piperidinyl)oxy]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

609767-45-5

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609767-45-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 609767-45-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,9,7,6 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 609767-45:
(8*6)+(7*0)+(6*9)+(5*7)+(4*6)+(3*7)+(2*4)+(1*5)=195
195 % 10 = 5
So 609767-45-5 is a valid CAS Registry Number.

609767-45-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[(3-chloro-4-fluoro-phenyl)amino]-6-(1-methyl-piperidin-4-yloxy)-7-methoxy-quinazoline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:609767-45-5 SDS

609767-45-5Downstream Products

609767-45-5Relevant academic research and scientific papers

USE OF QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL DISEASES

-

, (2011/11/30)

The present invention relates to the use of quinazoline derivatives, which show EGFR inhibitory activity, for the prevention and/or treatment of virus-induced diseases, preferably virus induced respiratory diseases and exacerbation in chronic airway diseases such as COPD or asthma.

Inhibitors of epidermal growth factor receptor tyrosine kinase: Optimisation of potency and in vivo pharmacokinetics

Ballard, Peter,Bradbury, Robert H.,Harris, Craig S.,Hennequin, Laurent F.A.,Hickinson, Mark,Kettle, Jason G.,Kendrew, Jane,Klinowska, Teresa,Ogilvie, Donald J.,Pearson, Stuart E.,Williams, Emma J.,Wilson, Ingrid

, p. 4908 - 4912 (2008/09/21)

The structure-activity and structure-property relationships of anilinoquinazoline inhibitors of EGFR were investigated. Strategies to lower volume of distribution and shorten half-life through structure and pKa modulation are discussed.

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