609769-12-2Relevant academic research and scientific papers
Selective hydrolysis of anti-1,3-diol-acetonides for the differentiation of 1,3-anti and 1,3-syn diols
Coste, Gérald,Gerber-Lemaire, Sandrine
, p. 671 - 674 (2006)
A mild and general method for the selective cleavage of anti-1,3-acetonides has been developed for the differentiation of 1,3-anti and 1,3-syn diols in long chain polyolic fragments. The diluted acidic conditions applied to these systems are compatible wi
New synthetic routes toward polyketide-like macrolides
Coste, Gérald,Gerber-Lemaire, Sandrine
, p. 685 - 688 (2007/10/03)
New pathways toward the synthesis of polyketide-like macrolides have been developed through the functionalization of long chain polyolic fragments readily obtained from 3,3′-methylenebis{[6-(benzyloxy)methoxy]cyclohept-3-en-1- ol} derivatives 6. This synt
An expeditious, non-iterative, and asymmetric synthesis of 3,5,7,9,11,13,15-heptahydroxypentadecanals
Gerber-Lemaire, Sandrine,Vogel, Pierre
, p. 2959 - 2963 (2007/10/03)
Ozonolysis of (1R,1′R,6R,6′R)-3,3′-methylenebis{6-[(benzyloxy) methoxy]cyclohept-3-en-1-ol} followed by the diastereoselective reduction of the resulting β-hydroxy ketone intermediates gives a rapid route to long-chain polyketides bearing unsymmetrical functions at their terminal positions. These can easily be converted into enantiomerically pure long-chain 1,3-polyol fragments. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
