609798-47-2

Upstream product

• 24544-04-5 2,6-diisopropylbenzenamine 
• 4755-77-5 Ethyl oxalyl chloride 

Downstream Products

• 1243262-73-8 C₂₀H₃₂N₂O₃ 
• 169772-26-3 2-[(2,6-diisopropylphenyl)amino]-2-oxoacetic acid 
• 1414649-05-0 (S)-N₁-(2,6-diisopropylphenyl)-N₂-(2-hydroxy-1-phenylethyl)oxalamide 
• 1358742-53-6 (S)-2-(2-(2,6-diisopropylphenylamino)ethylamino)-3-phenylpropan-1-ol 
• 1181445-39-5 (S)-1-(2,6-diisopropylphenyl)-3-(1-hydroxy-3-phenylpropan-2-yl)-4,5-dihydro-1H-imidazol-3-ium chloride 
• 1358742-52-5 (S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide 
• 889765-32-6 (S)-2-[2-(2,6-Diisopropyl-phenylamino)-ethylamino]-3-methyl-butan-1-ol 
• 920337-56-0 N-(2,6-diisopropyl-phenyl)-N'-(2,4,6-trimethyl-phenyl)-ethane-1,2-diamine 

Relevant academic research and scientific papers

Ruthenium metallacycles derived from 14-electron complexes. New insights into olefin metathesis intermediates

Ruthenium(IV) metallacycles derived from both ethylene and propene are reported. The propene-derived metallacycles represent the first observed examples of substituted ruthenacyclobutanes and offer new insight into the preferred stereochemical orientation

Steric factors on unsymmetrical O-hydroxyaryl N-Heterocyclic carbene ligands prevailing the stabilization of single stereoisomer of bis-ligated titanium complexes

Bis-ligated titanium (IV) metal complexes supported by bidentate unsymmetrical o-hydroxyaryl-substituted N-heterocyclic carbene ligands were synthesized and structurally identified. While the direct addition of the doubly deprotonated bulky imidazolidiniu

Efficient copper-catalyzed amination of DNA-conjugated aryl iodides under mild aqueous conditions

Herein, we describe the development of copper-catalyzed cross-coupling of DNA-conjugated aryl iodides with aliphatic amines. This protocol leverages a novel ligand, 2-((2,6-dimethoxyphenyl)amino)-2-oxoacetic acid, to effect the transformation in aqueous D

Synthesis of amino acid derived imidazolidinium salts as new NHC precatalysts

The preparation of new chiral symmetrically and unsymmetrically N,N′-disubstituted imidazolium based NHC salts Ib, IIb, IIIa-c and IVc-h from the amino acids l-proline and l-phenylalanine, is reported. Some preliminary tests have been carried out, demonstrating that the chiral NHCs give chiral induction in organometallic catalysis and can be used as organocatalysts.

Synthesis, crystal structures and magnetic properties of M IICuII chains (M=Mn and Co) with sterically hindered alkyl-substituted phenyloxamate bridging ligands

A series of neutral oxamato-bridged heterobimetallic chains of general formula [MCu(Lx)2(S)2]·p S·q H2O [p=0-1, q=0-2.5; L1=N-2,6-dimethylphenyloxamate, S=DMF with M=Mn (1 a) and Co (1 b); L2/su

Copper-catalyzed asymmetric addition of arylboronates to isatins: A catalytic cycle involving alkoxocopper intermediates

A copper-catalyzed addition of arylboronates to isatins has been developed to give 3-aryl-3-hydroxy-2-oxindoles under mild conditions. The catalytic cycle of this process has been examined through a series of stoichiometric reactions and an effective asymmetric variant has also been described by the use of a chiral N-heterocyclic carbene ligand.

New bidentate alkoxy-NHC ligands for enantioselective copper-catalysed conjugate addition

Chiral alkoxy-imidazolinium salts are easily available via a five-step procedure starting from β-aminoalcohols. This new family of alkoxy-N-heterocyclic carbene (NHC) precursors is shown to be highly active in the enantioselective copper-catalysed conjugate addition to cyclic enones. Complete conversion with low catalyst loading and good enantiomeric excesses up to 93% were obtained at room temperature.

Design and synthesis of new bidentate alkoxy-NHC ligands for enantioselective copper-catalyzed conjugate addition

A new family of chiral alkoxy-N-heterocyclic carbene (NHC) ligands has been designed for the enantioselective copper-catalyzed conjugate addition of dialkylzincs to enones. These new bidentate NHC ligands were synthesized in high overall yields using a five-step procedure starting from commercially available β-aminoalcohols. Influence of the temperature, base, solvent and copper source were studied in order to optimize the stereoselectivity of the addition. High reactivity and excellent enantioselectivity were obtained at ambient temperature with a range of cyclic enones and dialkylzinc. Addition to acyclic enones has also been studied.

Stable enols from Grignard addition to 1,2-diesters: Serendipity rules

The temperature-dependent formation of a remarkably stable enol from the reaction of EtMgBr with a 1,2-diester was accidentally discovered. This compound was spectroscopically characterized (1H and 13C NMR, IR), and both methyl carbo