609828-32-2

Upstream product

• 89046-67-3 (2S,3R)-2-methyl-1-(phenylmethoxy)hex-5-en-3-ol 

Downstream Products

• 609828-34-4 2-{6-[(1S)-1-methyl-2-(phenylmethoxy)ethyl]-(4S,2R,6R)-2-phenyl-(1,3-dioxan-4-yl)}-N-methoxy-N-methylacetamide 
• 609828-58-2 (2-{9-[9-(2-benzyloxy-1-methyl-ethyl)-6,10-dioxa-spiro[4.5]dec-7-ylmethyl]-6,10-dioxa-spiro[4.5]dec-7-yl}-1-{9-[4-(4-methoxy-benzyloxy)-3,5-dimethyl-hex-1-enyl]-6,10-dioxa-spiro[4.5]dec-7-ylmethyl}-ethoxy)-tert-butyl-dimethyl-silane 
• 609828-69-5 2-{9-[9-(2-(tert-butyl-dimethyl-silanyloxy)-3-{9-[4-(4-methoxy-benzyloxy)-3,5-dimethyl-hex-1-enyl]-6,10-dioxa-spiro[4.5]dec-7-yl}-propyl)-6,10-dioxa-spiro[4.5]dec-7-ylmethyl]-6,10-dioxa-spiro[4.5]dec-7-yl}-propan-1-ol 
• 609828-56-0 7-(9-{(1E)(3S,4S)-4-[(4-methoxyphenyl)methoxy]-3,5-dimethylhex-1-enyl}(7S,9R)-6,10-dioxospiro[4.5]dec-7-yl)-1-{9-[(1S)-1-methyl-2-(phenylmethoxy)ethyl](7S,9R)-6,10-dioxaspiro[4.5]dec-7-yl}(4S,6S)-4-hydroxy-6-(tert-butyldimethylsilyloxy)heptan-2-one 
• 609828-36-6 2-{9-[(1R)-1-methyl-2-(benzyloxy)ethyl]-(9S,7R)-6,10-dioxaspiro[4.5]dec-7-yl}-N-methoxy-N-methylacetamide 
• 609828-38-8 1-{9-[(1R)-1-methyl-2-(phenylmethoxy)ethyl]-(9S,7R)-6,10-dioxaspiro[4.5]dec-7-yl}acetone 
• 609828-66-2 (3S,5R,6S)-7-Benzyloxy-3,5-dihydroxy-6-methyl-heptanoic acid methoxy-methyl-amide 

Relevant academic research and scientific papers

Synthesis of the antifungal macrolide antibiotic (+)-roxaticin

The total synthesis of the antifungal macrolide antibiotic roxaticin has been accomplished. The synthesis relies principally on aldol and directed reduction steps to construct the extended 1,3-polyol array present in the natural product. Three principal n