60983-81-5

Basic information

• Product Name: 2-(HYDROXYAMINO)-2-METHYLPROPANAL OXIME
• Synonyms: 2-HYDROXYAMINO-2-METHYLPROPAN-1-AL OXIME;2-(HYDROXYAMINO)-2-METHYLPROPANAL OXIME;N-(2-HYDROXIMINO-1,1-DIMETHYLETHYL)-HYDROXYLAMINE
• CAS NO: 60983-81-5
• Molecular Formula: C₄H₁₀N₂O₂
• Molecular Weight: 118.13
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 60983-81-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 98-100°C
• Boiling Point: 267°C at 760 mmHg
• Flash Point: 115.2°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 0.00114mmHg at 25°C
• Refractive Index: 1.467
• CAS DataBase Reference: 2-(HYDROXYAMINO)-2-METHYLPROPANAL OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(HYDROXYAMINO)-2-METHYLPROPANAL OXIME(60983-81-5)
• EPA Substance Registry System: 2-(HYDROXYAMINO)-2-METHYLPROPANAL OXIME(60983-81-5)

Safety Data

• Hazard Codes: Xi
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3261
• Hazardous Substances Data: 60983-81-5(Hazardous Substances Data)

Usage

Functional group

Oxime (an oxygen-nitrogen double bond connected to a carbon atom)

Usage

Organic synthesis, reagent for the formation of oxime ethers

Value in pharmaceutical industry

Preparation of various drugs and medicinal compounds

Utility in chemical research and analysis

Ability to react with various other compounds for the synthesis of new and unique chemical structures.

InChI:InChI=1/C4H10N2O2/c1-4(2,6-8)3-5-7/h3,6-8H,1-2H3/b5-3+

Upstream product

• 88571-73-7 2,2,5,5-tetramethyl-2,5-dihydropyrazine 1,4-dioxide 

Downstream Products

• 33455-68-4 1-hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-imidazole 3-oxide 
• 88571-73-7 2,2,5,5-tetramethyl-2,5-dihydropyrazine 1,4-dioxide 
• 107946-01-0 N-(2-hydroximino-1,1-dimethylethyl)-α-benzoylnitrone 
• 88571-67-9 3-hydroxy-2,2-dimethyl-2,3-dihydropyrazine 1,4-dioxide 

Relevant articles and documents

Preparation of 2,3- and 2,5-Dihydropyrazine 1,4-Dioxides from 2-Hydroxyamino-2-methylpropanal Oxime and Some of Their Properties

3-Hydroxy-2,3-dihydropyrazine 1,4-dioxide derivatives were obtained by condensation of 2-hydroxyamino-2-methylpropanal oxime with glyoxal, diacetyl, and 1,2-cyclohexanedione in water, and 3-methoxy-2,3-dihydropyrazine 1,4-dioxide was obtained by condensation with diacetyl in methanol. 2,5-Dihydropyrazine 1,4-dioxide is formed when 2-hydroxyamino-2-methylpropanal oxime is heated in a solution of acetone and dilute hydrochloric acid.The reduction of 3-hydroxy- and 3-methoxy-2,3-dihydropyrazine 1,4-dioxides and 2,5-dihydropyrazine 1,4-dioxide leads to 1,4-dihydroxypiperazines, and the bromination of 3-methoxy-2,3-dihydropyrazine 1,4-dioxide gives 5,6-bis(bromomethyl)-3-methoxy-2,3-dihydropyrazine 1,4-dioxide. 1,4-Dihydroxy-2,5-piperazinedione was obtained by oxidation of 2,5-dihydropyrazine 1,4-dioxide.