60987-26-0Relevant academic research and scientific papers
Synthesis of aza-fused polycyclic quinolines through copper-catalyzed cascade reactions
Cai, Qian,Li, Zhengqiu,Wei, Jiajia,Fu, Liangbin,Ha, Chengyong,Pei, Duanqing,Ding, Ke
, p. 1500 - 1503 (2010)
Figure Presented A new and efficient method for the synthesis of aza-fused polycyclic qulnollnes (e.g., benzimidazo[1,2-a]quinolines) is described. This protocol includes an intermolecular condensation followed by a copper-catalyzed intramolecular C-N coupling reaction. The method is applied to a wide range of 2-iodo, 2-bromo, and 2-chloro aryl aldehyde substrates to yield the aza-fused polycyclic qulnollnes In good yields.
