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61-73-4

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Product FOB Price Min.Order Supply Ability Supplier
Methylene Blue/ Basic Blue 9
Cas No: 61-73-4
No Data 100 Gram 2 Metric Ton/Month Wuhan Kemi-Works Chemical Co., Ltd Contact Supplier
Factory supply Methylene Blue >99%
Cas No: 61-73-4
USD $ 99.0-100.0 / Kilogram 1 Kilogram 10 Metric Ton/Day Toda Biotechnology Co., Limited. Contact Supplier
Basic Blue 9 Manufacturer/High quality/Best price/In stock
Cas No: 61-73-4
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
Basic Blue 9
Cas No: 61-73-4
USD $ 1.0-3.0 / Kilogram 1 Kilogram 10 Kilogram/Day Hebei yanxi chemical co.,LTD. Contact Supplier
methylene blue manufacturer/supplier
Cas No: 61-73-4
No Data 1 Gram 1000 Metric Ton/Month Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd Contact Supplier
Basic Blue 9
Cas No: 61-73-4
No Data 1 Kilogram 1000 Metric Ton/Year Hefei TNJ chemical industry co.,ltd Contact Supplier
Factory price Cosmetic BASIC BLUE 9 61-73-4 Manufacturer
Cas No: 61-73-4
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Factory Supply Methylene Blue
Cas No: 61-73-4
No Data 1 1 Ality Chemical Corporation Contact Supplier
Factory Supply High Purity 99% Methylene Blue Powder
Cas No: 61-73-4
USD $ 90.0-100.0 / Kilogram 1 Kilogram 1000 Kilogram/Week Shaanxi Yuantai Biological Technology Co., Ltd. Contact Supplier
Methylene Blue Manufacturer CAS:61-73-4
Cas No: 61-73-4
No Data 10 Gram 10000 Metric Ton/Month Hubei XinRunde Chemical Co., Ltd Contact Supplier

61-73-4 Usage

Clinical Use

Methylene blue is 3,7-bis(dimethylamino)-phenazathioniumchloride (Urised). The compound occurs as a dark greencrystalline powder with a metallic appearance that is solublein water (1:25) and alcohol (1:65).Methylene blue has weak antiseptic properties that makeit useful for the treatment of cystitis and urethritis. The actionof methylene blue is considered to be bacteriostatic.The compound colors the urine and stool blue green.

Purification Methods

Crystallise the chloride from 0.1M 664 2HCl (16mL/g), the crystals are separated by centrifugation, washed with chilled EtOH and diethyl ether, and dried under vacuum. Crystallise it from 50% aqueous EtOH, wash it with absolute EtOH, and dry it at 50-55o for 24hours. It has also been crystallised from *benzene/MeOH (3:1). It has been salted out with NaCl from a commercial concentrated aqueous solution, then crystallised from water, and dried at 100o in an oven for 8-10hours. [Beilstein 27 III/IV 5152.]

Uses

A useful inhibitor of cGMP-mediated processes and a useful stain

Biological Activity

Biological stain and redox indicator. Inhibits tau filament formation (IC 50 = 1.9 μ M). Also inhibits soluble guanylyl cyclase.

Veterinary Drugs and Treatments

Methylene blue is used primarily for treating methemoglobinemia secondary to oxidative agents (nitrates, chlorates) in ruminants. It is also employed occasionally as adjunctive or alternative therapy for cyanide toxicity. Intra-operative methylene blue is also being used to preferentially stain islet-cell tumors of the pancreas in dogs in order to aid in their surgical removal or in determining the animal’s prognosis.

Chemical Properties

green fine crystalline powder

Definition

ChEBI: An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.

Hazard

Toxic by ingestion.

Safety Profile

Poison by ingestion,intraperitoneal, intravenous, and subcutaneous routes.Human systemic effects: cyanosis, blood changes.Experimental reproductive effects. Mutation datareported. When heated to decomposition it emits verytoxic fumes of NOx, SOx, and
InChI:InChI=1/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1

61-73-4 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (A5105)  Methylene Blue [Ion association reagent for spectrophotometric analysis]  >98.0%(T) 61-73-4 1g 345.00CNY Detail
TCI America (M0501)  Methylene Blue Hydrate  >70.0%(W) 61-73-4 25g 200.00CNY Detail
TCI America (M2392)  Methylene Blue Solution (Methanol Solution) [for Cell Staining]   61-73-4 100mL 520.00CNY Detail
Sigma-Aldrich (50484)  MethyleneBluesolution  for microbiology 61-73-4 50484-100ML-F 243.36CNY Detail
Sigma-Aldrich (77515)  MethyleneBluesolution  for microscopy 61-73-4 77515-100ML-F 432.90CNY Detail
Sigma-Aldrich (Y0001744)  Methylthioninium for system suitability  EuropePharmacopoeia (EP) Reference Standard 61-73-4 Y0001744 1,880.19CNY Detail

61-73-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name methylene blue

1.2 Other means of identification

Product number -
Other names Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61-73-4 SDS

61-73-4Synthetic route

sodium hexacyanoferrate(II)

sodium hexacyanoferrate(II)

methylene blue
61-73-4

methylene blue

A

sodium hexacyanoferrate(III)

sodium hexacyanoferrate(III)

B

Leuco-Methylenblau
613-11-6

Leuco-Methylenblau

Conditions
ConditionsYield
With hydrogenchloride Kinetics; UV;
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