61000-46-2Relevant academic research and scientific papers
(Acylaryloxy)acetic Acid Diuretics. 4. Indenofuran-2-carboxylic Acids
Woltersdorf, Otto W.,Solms, S. Jane de,Cragoe, Edward J
, p. 874 - 878 (2007/10/02)
Investigation of the chemistry of the potent new uricosuric, diuretic indacrinone (MK-196) led to a class of novel annulated derivatives, indenofuran-2-carboxylic acids.The structural requirements for optimal diuretic and uricosuric activity of the
6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids
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, (2008/06/13)
6-Oxo-7,7-disubstituted-1,2,7,8-tetrahydro (and 7,8-dihydro)-6H-indeno-[5,4-b]furan (and thiophene)carboxylic acids, the salt, ester and amide derivatives thereof and combinations of these compounds with antikaluretic agents are disclosed having diuretic-saluretic, uricosuric and antihypertensive activity.
