61001-10-3Relevant academic research and scientific papers
Facile three-component domino reactions for the synthesis of 2-arylimidazo[1,2-a]pyridines and 2-arylimidazo[2,1-a]isoquinolines
Prasanna, Pitchaimani,Kumar, Sundaravel Vivek,Gunasekaran, Pethaiah,Perumal, Subbu
supporting information, p. 3740 - 3743 (2013/07/05)
The three-component domino reactions of pyridine/isoquinoline, phenacyl bromide, and substituted (E)-N-hydroxyarylimidoyl chloride in the presence of triethylamine afforded a series of 2-arylimidazo[1,2-a]pyridines and 2-arylimidazo[2,1-a]isoquinolines. This one pot three-component transformation presumably proceeds via ylide generation/annulation/fragmentation/dehydration domino sequence of reactions.
Synthesis and pregnancy terminating activity of 2-arylimidazo[2,1-a]isoquinolines and isoindoles
Toja,Omodei Sale,Favara,Omodei-Sale,Cattaneo,Gallico,Galliani
, p. 1222 - 1226 (2007/10/02)
A series of 2-arylimidazo[2,1-a]isoquinolines (1-21), some 5,6-dihydro derivatives (22-28) and 2-phenyl-5H-imidazo[2,1-a]isoindole (29) were synthesized and tested for the pregnancy terminating activity in hamsters and rats. An efficient preparation of 2-
