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4-Aminobenzenesulfonamide hydrochloride (4-ABS) is a chemical compound that belongs to the sulfonamide class of antibiotics. It is a bacteriostatic agent that inhibits the growth of various bacteria by interfering with their synthesis of folic acid. 4-ABS works by competing with para-aminobenzoic acid for the enzyme dihydropteroate synthase, which disrupts the production of dihydrofolic acid and subsequently inhibits the biosynthesis of purines and pyrimidines. This can ultimately lead to the inhibition of bacterial growth and proliferation. In addition to its antibacterial properties, 4-ABS has also been investigated for its potential use in the treatment of certain types of cancer and systemic lupus erythematosus.

6101-31-1

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6101-31-1 Usage

Uses

Used in Pharmaceutical Industry:
4-ABS is used as a bacteriostatic agent for inhibiting the growth of various bacteria. It is effective in treating bacterial infections by disrupting the synthesis of folic acid, which is essential for bacterial growth and proliferation.
Used in Cancer Treatment Research:
4-ABS is being investigated for its potential use in the treatment of certain types of cancer. Its mechanism of action in inhibiting the biosynthesis of purines and pyrimidines may have therapeutic benefits in cancer treatment.
Used in Systemic Lupus Erythematosus Treatment Research:
4-ABS has also been explored for its potential use in the treatment of systemic lupus erythematosus, an autoimmune disease. Its antibacterial properties and potential anti-inflammatory effects may contribute to the management of this condition.

Check Digit Verification of cas no

The CAS Registry Mumber 6101-31-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,0 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6101-31:
(6*6)+(5*1)+(4*0)+(3*1)+(2*3)+(1*1)=51
51 % 10 = 1
So 6101-31-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O2S.ClH/c7-5-1-3-6(4-2-5)11(8,9)10;/h1-4H,7H2,(H2,8,9,10);1H

6101-31-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-AMINOBENZENESULPHONAMIDE HCL

1.2 Other means of identification

Product number -
Other names sulfanilamide*HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6101-31-1 SDS

6101-31-1Relevant academic research and scientific papers

A facile and efficient method for the selective deacylation of N-arylacetamides and 2-chloro-Narylacetamides catalyzed by SOCl2

Wang, Gong-Bao,Wang, Lin-Fa,Li, Chao-Zhang,Sun, Jing,Zhou, Guang-Ming,Yang, Da-Cheng

experimental part, p. 77 - 89 (2012/05/20)

Thionyl chloride efficiently and selectively promoted the deacylation of N-arylacetamides and 2-chloro-N-arylacetamides, under anhydrous conditions, without effecting the ester group, aminosulfonyl group, or benzyloxyamide group. This method, which has been successfully applied to a variety of substrates including different N-arylacetamides and 2-chloro-N-arylacetamides, has the attractive advantages of inexpensive reagents, satisfactory selectivity, excellent yields, short reaction time, and convenient workup. This new method can probably be used to selectively deacylate between aromatic amides and alkyl amides. Springer Science+Business Media B.V. 2011.

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