61020-45-9Relevant academic research and scientific papers
Synthesis of N-Alkylated Indolines and Indoles from Indoline and Aliphatic Ketones
Bayindir, Sinan,Erdogan, Esra,Kilic, Haydar,Aydin, Omer,Saracoglu, Nurullah
supporting information, p. 1589 - 1594 (2015/10/06)
A survey of redox aminations of indoline with aliphatic ketones using bismuth nitrate as catalyst is described. A reaction of an equivalent amount of indoline and aliphatic cyclic and acyclic ketones provides a mixture of excessive alkylated indole derivatives over typically redox isomerization and reductive alkylation pathways while using of the five equivalent of indoline provides N-alkylated indolines as a reductive alkylation product. The desired N-alkyl indoles from the oxidation of N-alkyl indolines were obtained in excellent yields.
