610300-87-3

Upstream product

• 4559-70-0 Diphenylphosphine oxide 
• 253783-11-8 (1R,4R)-2-(6-phenylpyridin-2-yl)-1,7,7-trimethylbicyclo[2.2.1]-2-heptene 
• 108450-08-4 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-en-2-yl trifluoromethanesulfonate 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 
• 98-80-6 phenylboronic acid 
• 253783-09-4 (1R,4R)-2-(6-bromopyridin-2-yl)-1,7,7-trimethylbicyclo[2.2.1]-2-heptene 

Downstream Products

• 610300-74-8 2-[(1S,2S,3R,4S)-3-(diphenylphosphino)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl]-6-phenylpyridine 

Relevant academic research and scientific papers

t-BuOK-mediated hydrophosphination of functionalized alkenes: A novel synthesis of chiral P,N- and P,P-ligands

A novel synthesis of effective chiral P,N- and P,P-ligands has been developed by using a t-BuOK-mediated hydrophosphination of chiral alkenylpyridines and alkenylphosphine oxides. Ir complexes of chiral P,N-ligands 1 and 3 gave high enantioselectivities for the hydrogenation of (Z)-α-(acetamido)cinnamate 25 and (E)-1,2-diphenylpropene leading to the hydrogenated products with up to 97% ee.

CHIRAL LIGANDS AND THEIR TRANSITION METAL COMPLEXES

The invention relates to chiral phosphorus compounds and their transition metal complexes, in addition to the use of said transition metal complexes, in particular in asymmetric syntheses.