610314-47-1

Upstream product

• 875121-92-9 (R)-2-[(2-Chloro-acetyl)-(4-methoxy-benzyl)-amino]-3-phenyl-propionic acid methyl ester 
• 344765-12-4 (S)-methyl 2-(2-chloro-N-(4-methoxybenzyl)acetamido)-3-phenylpropanoate 
• 909713-13-9 (p-methoxybenzyl)-D-Phe-OMe 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 21685-51-8 D-phenylalanine methyl ester 
• 344765-03-3 2-(4-methoxybenzylamino)-3-phenypropionic acid methyl ester 

Downstream Products

• 439589-35-2 (R)-2-Benzyl-1-(4-methoxy-benzyl)-4-oxo-azetidine-2-carboxylic acid 
• 681456-98-4 (R)-methyl 1-(4-methoxybenzyl)-2-benzylazetidine-2-carboxylate 

Relevant academic research and scientific papers

β-Lactams derived from phenylalanine and homologues: effects of the distance between the aromatic rings and the α-stereogenic reactive center on the memory of chirality

The enantioselectivity in the base-promoted cyclization of N-chloroacetyl derivatives of Phe, Phg, and Hph is dependent on the side-chain length, with the best results for Phg analogues (up to 74% ee). In contrast, shortening of the N-substituent, from a

Stereoselective synthesis of amino acid-derived β-lactams. Experimental evidence for TADDOL as a memory of chirality enhancer

In model experiments, concerning the modulation of memory of chirality during the intramolecular alkylation of N-(p-methoxy)benzyl-N-chloroacetyl-Phe- OtBu derivative to the corresponding β-lactam, TADDOL was selected from a panel of different