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Papulacandin B is a carbohydrate-containing antibiotic derived from the deuteromycetous fungus Papularia sphaerosperma. It is a variant of papulacandin A, with a distinct (2E,4Z,6E)-8-hydroxydeca-2,4,6-trienoyl chain replacing the (2E,4E)-deca-2,4-dienoyl chain at the O-(6') position. This modification endows Papulacandin B with potent antifungal properties, particularly against Candida albicans.
Used in Pharmaceutical Industry:
Papulacandin B is used as an antifungal agent for its potent activity against Candida albicans, a common fungal pathogen responsible for various infections in humans. Its unique structure and efficacy make it a valuable candidate for the development of new antifungal drugs to combat Candida-related infections.
Used in Research and Development:
In the field of microbiology and pharmaceutical research, Papulacandin B serves as a crucial tool for studying the mechanisms of antifungal action and resistance. Its potent activity against Candida albicans allows researchers to investigate the fungus's vulnerabilities and develop novel strategies for combating drug-resistant strains.
Used in Agricultural Industry:
Papulacandin B can be utilized as a biopesticide to protect crops from fungal infections caused by Candida species. Its targeted antifungal properties can help reduce crop losses and improve agricultural productivity while minimizing the environmental impact of chemical fungicides.
Used in Food Preservation:
In the food industry, Papulacandin B has the potential to be employed as a natural preservative to prevent spoilage caused by fungal contamination. Its ability to inhibit the growth of Candida albicans and other fungi can help extend the shelf life of perishable food products, ensuring food safety and quality.

61032-80-2

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61032-80-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 61032-80-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,0,3 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 61032-80:
(7*6)+(6*1)+(5*0)+(4*3)+(3*2)+(2*8)+(1*0)=82
82 % 10 = 2
So 61032-80-2 is a valid CAS Registry Number.

61032-80-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name papulacandin B

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61032-80-2 SDS

61032-80-2Upstream product

61032-80-2Downstream Products

61032-80-2Related news

Effect of Papulacandin B (cas 61032-80-2) and calcofluor white on the incorporation of mannoproteins in the wall of Candida albicans blastospores07/12/2019

Incorporation of mannoproteins into the walls of Candida albicans blastospores (yeast phase) was followed by continuous lebelling and pulse-chase experiments. The effect in the process of compounds that interfere with synthesis (papulacandin B) or assembly (calcofluor white) of structural polyme...detailed

Tunicamycin and Papulacandin B (cas 61032-80-2) inhibit incorporation of specific mannoproteins into the wall of Candida albicans regenerating protoplasts07/11/2019

Regeneration of Candida albicans protoplasts began with the formation of a chitin network which was complemented after a lag of about 60 min by the deposition of β-glucan. Proteins were incorporated early to the growing structure, beginning with the mannoproteins which are kept in place by non-...detailed

61032-80-2Relevant academic research and scientific papers

Papulacandin derivatives and pharmaceutical compositions containing same

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, (2008/06/13)

The new antibiotic "Papulacandin" is obtained by the cultivation of the microorganism Papularia sphaerosperma (Pers.) Hohnel, especially of the strain NRRL 8086, under aerobic conditions in an aqueous nutrient medium. There can also be used mutants of said microorganisms. Papulacandin consists of various components A, B, C, D and E, the more important of which are A and B, whose structures have been elucidated to a great extent: they contain only carbon, hydrogen and oxygen. Papulacandin and its components have a strong anti-fungal action, for instance against Candida albicans, and can be used for combating infections caused by pathogenic fungi.

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