61039-53-0Relevant articles and documents
Modulation of the Kynurenine Pathway in Search for New Neuroprotective Agents. Synthesis and Preliminary Evaluation of (m-Nitrobenzoyl)alanine, a Potent Inhibitor of Kynurenine-3-hydroxylase
Pellicciari, Roberto,Natalini, Benedetto,Costantino, Gabriele,Mahmoud, Mahmoud R.,Mattoli, Luisa,et al.
, p. 647 - 655 (1994)
The synthesis of (o-nitrobenzoyl)-, (m-nitrobenzoyl)-, and (p-nitrobenzoyl)alanine (o-, m-, and p-NBA), three new kynurenine analogues, and their evaluation as inhibitors of kynureninase and kynurenine-3-hydroxylase are reported.The most potent of these c
