61043-35-4

Basic information

• Product Name: benzyloxycarbonylalanyl-alanyl-phenylalanine-4-nitroanilide
• Synonyms: benzyloxycarbonylalanyl-alanyl-phenylalanine-4-nitroanilide
• CAS NO: 61043-35-4
• Molecular Formula: C₂₉H₃₁N₅O₇
• Molecular Weight: 561.5857
• Mol File: 61043-35-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 862.9°Cat760mmHg
• Flash Point: 475.7°C
• Appearance: /
• Density: 1.307g/cm³
• Vapor Pressure: 3.64E-30mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: benzyloxycarbonylalanyl-alanyl-phenylalanine-4-nitroanilide(CAS DataBase Reference)
• NIST Chemistry Reference: benzyloxycarbonylalanyl-alanyl-phenylalanine-4-nitroanilide(61043-35-4)
• EPA Substance Registry System: benzyloxycarbonylalanyl-alanyl-phenylalanine-4-nitroanilide(61043-35-4)

Safety Data

• Hazardous Substances Data: 61043-35-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C29H31N5O7/c1-19(30-26(35)20(2)31-29(38)41-18-22-11-7-4-8-12-22)27(36)33-28(37)25(17-21-9-5-3-6-10-21)32-23-13-15-24(16-14-23)34(39)40/h3-16,19-20,25,32H,17-18H2,1-2H3,(H,30,35)(H,31,38)(H,33,36,37)/t19-,20-,25-/m0/s1

Upstream product

• 16012-70-7 benzyloxycarbonyl-L-alanyl-L-alanine 
• 2360-97-6 L-phenylalanine-p-nitroanilide 

Relevant articles and documents

Biocatalytic properties of thermolysin immobilized on polyvinyl alcohol cryogel

Preparations with different contents of thermolysin were obtained by the immobilization of the enzyme on granulated polyvinyl alcohol cryogel. Their activity and stability in an aqueous medium and in mixtures of polar organic solvents of different composition were investigated. The catalytic properties of the preparations in reactions of peptide bond formation were studied, and the optimal amount of the biocatalyst, the concentrations of initial reagents, and the ratios of organic solvents and water necessary for effective enzymatic peptide synthesis catalyzed by immobilized thermolysin were determined. A series of peptides of the general formula Z-Ala-Ala-Xaa-pNA, where Xaa = Leu, Ile, Phe, Val, or Ala, were synthesized, and the immobilized enzyme was shown to retain substrate specificity in an organic medium.