61053-16-5

Basic information

• Product Name: 1,2-Dimethyl-1H-Imidazole-4,5-Dicarbonitrile
• Synonyms: 1,2-Dimethyl-1H-Imidazole-4,5-Dicarbonitrile;1H-Imidazole-4,5-dicarbonitrile, 1,2-dimethyl-;1,2-dimethylimidazole-4,5-dicarbonitrile;1,2-Dimethyl-1H-Imidazole-4,5-Dicarbonitrile(WXC00777)
• CAS NO: 61053-16-5
• Molecular Formula: C7H6N4
• Molecular Weight: 146.14934
• Mol File: 61053-16-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Dimethyl-1H-Imidazole-4,5-Dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Dimethyl-1H-Imidazole-4,5-Dicarbonitrile(61053-16-5)
• EPA Substance Registry System: 1,2-Dimethyl-1H-Imidazole-4,5-Dicarbonitrile(61053-16-5)

Safety Data

• Hazardous Substances Data: 61053-16-5(Hazardous Substances Data)

Usage

Appearance

White to off-white powder

Solubility

Insoluble in water, soluble in organic solvents

Uses

Building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds

Potential applications

Corrosion inhibitor, electrochemical sensors, materials for organic solar cells

Stability

Stable under normal conditions

Safety precautions

Handle and store with proper precautions to prevent potential hazards

Upstream product

• 1445-45-0 Trimethyl orthoacetate 
• 1187-42-4 diaminomaleonitrile 
• 69240-56-8 4-(4-bromophenoxy)benzaldehyde 
• 40056-53-9 2-methyl-1H-imidazole-4,5-dicarbonitrile 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 122222-09-7 1,2-dimethyl-1H-imidazole-5-carboxylic acid 

Relevant articles and documents

5-MEMBERED HETEROARYL CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV

The present disclosure provides, in part, 5-membered heteroaryl carboxamide compounds, and pharmaceutical compositions thereof, useful for disruption of HBV core protein assembly, and methods of treating Hepatitis B (HBV) infection.

1-Alkylation of 4,5-dicyanoimidazole by ortho esters

Reexamination of the reaction of ortho esters with diaminomaleonitrile (1) or 4,5-dicyanoimidazole (3a) revealed that 1-alkyl-4,5-dicyanoimidazoles 4a-f can be obtained in high yield in a one-pot procedure without any additional reagent. This simple procedure is economically competitive with other known methods. Several products previously reported for similar reactions have been shown to be the imidates of diaminomaleonitrile, 2b and 7.