61071-65-6 Usage
Chemical structure
1H-Isoindole-1,3(2H)-dione, 2-(2-oxo-3-piperidinyl)-, (S)is a chemical compound that contains a piperidinyl group and an isoindole-1,3-dione core structure.
Enantiomers
It exists as a single enantiomer, with the (S)configuration.
Class of compounds
It belongs to the class of heterocyclic compounds, which are organic compounds containing a ring structure made up of atoms of at least two different elements, such as oxygen, nitrogen, or sulfur.
Potential applications
It may have potential applications in pharmaceuticals, as the piperidine moiety is commonly found in a variety of bioactive compounds.
Specific use and properties
The specific use and properties of 1H-Isoindole-1,3(2H)-dione, 2-(2-oxo-3-piperidinyl)-, (S)would depend on the context and purpose for which it is being employed.
Check Digit Verification of cas no
The CAS Registry Mumber 61071-65-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,0,7 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 61071-65:
(7*6)+(6*1)+(5*0)+(4*7)+(3*1)+(2*6)+(1*5)=96
96 % 10 = 6
So 61071-65-6 is a valid CAS Registry Number.
61071-65-6Relevant academic research and scientific papers
Phi, Thi Dao,Mai, Huong Doan Thi,Tran, Van Hieu,Vu, Van Loi,Truong, Bich Ngan,Tran, Tuan Anh,Chau, Van Minh,Pham, Van Cuong
, p. 1830 - 1833 (2017)
A series of bengamide E analogues were prepared from the corresponding polyketide chain and amino acids via amide coupling reactions. Opening of the polyketide chain lactone ring with α-aminolactams was successfully achieved under microwave irradiation in the presence of sodium 2-ethyl hexanoate. A cytotoxic activity evaluation against a panel of cancer cell lines (KB, HepG-2, Lu-1, MCF-7, HL-60 and Hela) indicated that the 2′R analogues were generally more cytotoxic than the 2′S analogues. Additionally, several analogues exhibited selective inhibition against various cancer cell lines: compounds 32a and 32b selectively inhibited MCF-7 cells, while 33b and 35b were more sensitive toward Lu-1 and HepG-2, respectively. Notably, some of the synthetic analogues possess cytotoxic activities with IC50 values less than 1?μM.
