610755-99-2Relevant academic research and scientific papers
Combining Q2MM modeling and kinetic studies for refinement of the osmium-catalyzed asymmetric dihydroxylation (AD) mnemonic
Fristrup, Peter,Jensen, Gitte Holm,Andersen, Marie Louise Nygaard,Tanner, David,Norrby, Per-Ola
, p. 2182 - 2198 (2007/10/03)
The interactions between the substrate and the ligand in the Sharpless AD reaction have been examined in detail, using a combination of substrate competition experiments and molecular modeling of transition states. There is a good agreement between comput
Palladium-catalyzed negishi cross-coupling reactions of unactivated alkyl iodides, bromides, chlorides, and tosylates
Zhou, Jianrong,Fu, Gregory C.
, p. 12527 - 12530 (2007/10/03)
A single method (2% Pd2(dba)3/8% PCyp 3/NMI in THF/NMP at 80°C; Cyp = cyclopentyl) achieves the cross-coupling of a range of β-hydrogen-containing primary alkyl iodides, bromides, chlorides, and tosylates with an array of alkyl-, alkenyl-, and arylzinc halides. The process is compatible with a variety of functional groups, including esters, amides, imides, nitriles, and heterocycles.
