610796-29-7

Upstream product

• 77152-98-8 3-<<(benzyloxy)carbonyl>amino>propiothioamide 
• 610796-27-5 (R)-3-Benzyloxycarbonylamino-5-bromo-4-oxo-pentanoic acid 
• 118248-05-8 Z-D-Asp(OBut)-CHN₂ 
• 71449-08-6 (2R)-2-{[(benzyloxy)carbonyl]amino}-4-tert-butoxy-4-oxobutanoic acid 

Downstream Products

• 610796-31-1 {(R)-1-[2-(2-Benzyloxycarbonylamino-ethyl)-thiazol-4-yl]-2-[methyl-(4-oxo-2-ureido-1,4,5,6-tetrahydro-pyrimidin-5-yl)-carbamoyl]-ethyl}-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Pyrimidinone antibiotics - Heterocyclic analogues with improved antibacterial spectrum

We report the synthesis and pharmacological evaluation of new derivatives of the natural dipeptide antibiotic TAN 1057 A,B containing heterocycles either in the β-amino acid side chain or as mimics of the urea function. In the course of this program, we identified novel analogues that display activity towards a broader panel of Gram-positive bacteriae.