611209-91-7

Upstream product

• 3417-91-2 L-tyrosine methyl ester HCl 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 611209-89-3 N-(benzyloxycarbonyl)-O-butyl-L-tyrosine methyl ester 

Downstream Products

• 611209-99-5 N-(benzyloxycarbonyl)-O-butyl-L-tyrosinal 
• 611210-23-2 (1S)-2-(4-butoxyphenyl)-1-(1,3-dioxolan-2-yl)ethanamine 
• 611210-39-0 (2S)-N-[(1S)-2-(4-butoxyphenyl)-1-(1,3-dioxolan-2-yl)ethyl]-2-hydroxy-4-methylpentanamide 
• 611210-11-8 N-((1S)-2-(4-butoxyphenyl)-1-(2,5-dioxolanyl)ethyl)(benzyloxy)formamide 

Relevant academic research and scientific papers

HYDROXYMORPHOLINONE DERIVATIVE AND MEDICINAL USE THEREOF

A compound represented by the following formula (I) wherein R1 and R2 are each a lower alkyl group optionally having substituents, which has a calpain inhibitory activity, or a salt thereof is provided.

Novel 6-Hydroxy-3-morpholinones as cornea permeable calpain inhibitors

A novel series of 6-hydroxy-3-morpholinones, in which the functional aldehyde and the hydroxy group of P2 site form a cyclic hemiacetal, was identified as calpain inhibitors. The placement of isobutyl group at the 2-position of the 3-morpholino