61147-36-2Relevant academic research and scientific papers
Conversion of cyclooxygenase inhibitors into hydroxythiazole 5-lipoxygenase inhibitors
Kerdesky, Francis A.J.,Brooks, Clint D.W.,Hulkower, Keren I.,Bouska, Jennifer B.,Bell, Randy L.
, p. 393 - 396 (2007/10/03)
Representative examples of NSAID cyclooxygenase inhibitors such as naproxen, ibufenac, ibuprofen, and butibufen have been transformed into 5-lipoxygenase inhibitors by replacement of the carboxylic acid moiety with a 4-hydroxythiazole group.
Phenylalkanoic compounds and therapeutic use thereof
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, (2008/06/13)
Novel phenylalkanoic compounds of the formula I STR1 wherein R1 and R2 independently from each other represent hydrogen or alkyl with 1 to 8 carbon atoms, salts of such compounds and salts thereof, therapeutic uses of the phenylalkanoic compounds, or of the pharmacologically safe salts thereof for treating inflammatory diseases, tussive states, pain symptoms and pyretic diseases and pharmaceutical composition containing the phenylalkanoic compounds or the pharmacologically safe salts together with a carrier and an optional adjuvant or additive.
