61164-72-5 Usage
Description
Methyl 2-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)acetate, also known as 1,2,3,4-tetrahydro-2-oxo-3-quinolineacetic acid methyl ester, is an organic compound with a quinoline-based structure. It is characterized by its potential applications in the pharmaceutical and chemical industries due to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
Methyl 2-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)acetate is used as an intermediate in the synthesis of 1H-2,3,3a,4-tetrahydro-2-oxopyrrolo[2,3-b]quinolines, which are compounds with hypotensive properties. These compounds have demonstrated the ability to decrease aortic blood pressure by up to 34% in rats after 30 minutes of administration, making them promising candidates for the development of antihypertensive drugs.
Used in Chemical Synthesis:
Methyl 2-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)acetate is also used as a reagent in the preparation of bicyclic compounds and compositions. These compounds have potential applications as PDF (Phosphodiesterase) inhibitors, which are important targets for the treatment of various diseases, including cardiovascular and respiratory disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 61164-72-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,1,6 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 61164-72:
(7*6)+(6*1)+(5*1)+(4*6)+(3*4)+(2*7)+(1*2)=105
105 % 10 = 5
So 61164-72-5 is a valid CAS Registry Number.
61164-72-5Relevant articles and documents
Hypotensive agents
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, (2008/06/13)
Optionally substituted 1-H-2,3,3a,4-Tetrahydro-2-oxopyrrolo[2,3-b]quinolines or the pharmaceutically acceptable salts thereof are compounds useful as blood platelet anti-aggregative and/or antihypertensive agents in mammals, including humans.