61189-21-7Relevant academic research and scientific papers
Thermal ring transformation of 2,2-disubstituted benzothiazoline 1- oxides
Shimizu,Kanematsu,Hashimoto,Kobayashi
, p. 73 - 79 (2007/10/03)
Thermal rearrangement of 2,2-disubstituted benzothiazoline 1-oxides (1) in aprotic solvent afforded the corresponding 1,4-benzothiazines (2) and (3). The thermal reaction performed in the presence of electron-deficient acetylenic compounds produced new tricyclic compounds (7) whose structures have been established by an X-Ray crystal structure determination.
Influence of Phenylthio and Alkylthio Substituents on the Reactivity of 1-Oxa-1,3-butadienes in Hetero Diels-Alder Reactions
Tietze, Lutz F.,Fennen, Jens,Wichmann, Juergen
, p. 1507 - 1512 (2007/10/02)
The synthesis of the cyclic enamino ketones 1-3 bearing an alkylthio or an phenylthio group and their reactivity in hetero Diels-Alder reactions with enol ethers is described.Only compound 3 with an phenylthio group undergoes a cycloaddition with 16a-d to afford the diastereomeric adducts 17a-d and 18a-d.To estimate the activation by a phenylthio and alkylthio group semiempirical PM3/RHF calculations of the frontier orbital energies and coefficients of different enamine carbaldehydes have been performed.Key Words: Enamino ketones / 1,4-Thiazines / Hetero Diels-Alder reactions / Pyrans, dihydro / Calculations, semiempirical
