612-53-3

Usage

Uses

Used in Pharmaceutical Industry:
3-IMINO-2-INDOLINONE is used as a potential anti-cancer agent for its possible role in combating cancer cells. Its unique structure allows it to be a candidate for further exploration and development in the field of oncology.
Used in Organic Synthesis:
3-IMINO-2-INDOLINONE is utilized as a building block in the synthesis of various organic compounds. Its reactivity and structural properties make it a valuable component in the creation of complex organic molecules.
Used in Agrochemicals:
3-IMINO-2-INDOLINONE is employed as a starting material or intermediate in the development of agrochemicals. Its potential applications in this industry highlight its versatility and importance in chemical research and product development.

InChI:InChI=1/C8H6N2O/c9-7-5-3-1-2-4-6(5)10-8(7)11/h1-4H,(H2,9,10,11)

Upstream product

• 1165809-20-0 indole-2,3-dione 3-thiosemicarbazone 
• 28492-94-6 isatin-3-(N⁴-benzylthiosemicarbazone) 

Downstream Products

• 86-96-4 1,2,3,4-tetrahydro-quinazoline-2,4-dione 
• 30932-74-2 N-carbamoyl-anthranilic acid amide 
• 91-56-5 indole-2,3-dione 
• 86-96-4 quinazoline-2,4-diol 
• 117069-75-7 3-aminoindolin-2-one 
• 1578230-19-9 (S)-methyl 2-(2,3-dioxoindolin-1-yl)-4-oxo-4-phenylbutanoate 
• 1261153-08-5 (E)-5-bromo-3-[[4-(methylsulfonyl)phenyl]methylene]indolin-2-one 
• 20870-79-5 5-nitrooxindole 
• 20870-78-4 5-bromo-2-indolin-2-one 

Relevant academic research and scientific papers

Electrochemical characterization of isatin-thiosemicarbazone derivatives

Abstract: Herein, we have notably described the electrochemical behavior of four isatin-thiosemicarbazone derivatives. In this regard, cyclic voltammograms of isatin-3-thiosemicarbazone (ITSC), isatin-3-(N4-benzylthiosemicarbazone) (ITSC-Ph), 1-(5-nitro-2-oxoindolin-3-ylidene)thiosemicarbazide (NO2-ITSC) and 1-(5-nitro-2-oxoindolin-3-ylidene)-4-phenylthiosemicarbazide (NO2-ITSC-Ph) have demonstrated an irreversible oxidation process. More specifically, the generation of isatin and thiourea moieties as the final oxidation products was proposed. The cyclic voltammograms also demonstrate irreversible reduction processes of ITSC and ITSC-Ph in three steps. The proposed final products are 3-aminoindolin-2-one and thiourea moieties. In the cyclic voltammograms of NO2-ITSC and NO2-ITSC-Ph, five reduction processes were observed: three of them due to reduction of the nitro group. It was proposed that the formation of 5-hydroxyamino-3-iminoindolin-2-one and the thiourea moieties would be the final products. Graphic abstract: [Figure not available: see fulltext.] Electrochemical characterization of four isatin thiosemicarbazone derivatives is described. The compounds are irreversibly oxidized and reduced. Isatin moieties and thiourea are proposed to be the products generated after oxidation. Considering the reduction processes, the nitro group present at the isatin moiety is also reduced and influences the reduction products generated.