6120-63-4

Basic information

• Product Name: (THR6)-BRADYKININ
• Synonyms: (THR6)-BRADYKININ;ARG-PRO-PRO-GLY-PHE-THR-PRO-PHE-ARG;H-ARG-PRO-PRO-GLY-PHE-THR-PRO-PHE-ARG-OH
• CAS NO: 6120-63-4
• Molecular Formula: C51H75N15O11
• Molecular Weight: 1074.24
• Mol File: 6120-63-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.48 g/cm³
• Refractive Index: 1.688
• Storage Temp.: -15°C
• PKA: 3.34±0.10(Predicted)
• CAS DataBase Reference: (THR6)-BRADYKININ(CAS DataBase Reference)
• NIST Chemistry Reference: (THR6)-BRADYKININ(6120-63-4)
• EPA Substance Registry System: (THR6)-BRADYKININ(6120-63-4)

Safety Data

• Hazardous Substances Data: 6120-63-4(Hazardous Substances Data)

Usage

Description

(Thr6)-Bradykinin is a derivative of Bradykinin, a pharmaceutical substance that is commonly used as a vasodilator. It is synthetically derived and exhibits the same response as Bradykinin, being very beneficial in the treatment of conditions such as hypertension. This potent biologically active peptide plays an important role in numerous physiological and pathophysiological processes, such as inflammation, pain induction, and blood pressure regulation.

Uses

Used in Pharmaceutical Industry:
(Thr6)-Bradykinin is used as a vasodilator for the treatment of hypertension. It works by stimulating the release of nitric oxide and prostacyclin in endothelial cells, which helps in the dilation of blood vessels, promoting increased blood flow and effectively managing blood pressure.
Used in Medical Research:
(Thr6)-Bradykinin is used as a research tool for studying the mechanisms of blood vessel dilation and the role of nitric oxide and prostacyclin in endothelial cells. This helps in understanding the underlying processes of various cardiovascular conditions and developing new therapeutic strategies.
Used in Inflammation and Pain Management:
(Thr6)-Bradykinin is used as a potential therapeutic agent for managing inflammation and pain. Its role in physiological and pathophysiological processes makes it a valuable compound for investigating the treatment of conditions associated with inflammation and pain.

InChI:InChI=1/C51H75N15O11/c1-30(67)41(48(75)65-25-11-20-38(65)45(72)62-36(28-32-15-6-3-7-16-32)42(69)61-34(49(76)77)18-9-23-58-51(55)56)63-43(70)35(27-31-13-4-2-5-14-31)60-40(68)29-59-44(71)37-19-10-24-64(37)47(74)39-21-12-26-66(39)46(73)33(52)17-8-22-57-50(53)54/h2-7,13-16,30,33-39,41,67H,8-12,17-29,52H2,1H3,(H,59,71)(H,60,68)(H,61,69)(H,62,72)(H,63,70)(H,76,77)(H4,53,54,57)(H4,55,56,58)/t30-,33+,34+,35+,36+,37+,38+,39+,41+/m1/s1