61201-31-8

Upstream product

• 119-61-9 benzophenone 
• 84531-04-4 2-lithio-1,3-butadiene 
• 108-86-1 bromobenzene 
• 30332-99-1 penta-3,4-dienoic acid ethyl ester 
• 934009-26-4 [2-(2,2-dibromovinyl)-1-phenylcyclopropyl]benzene 
• 59591-01-4 2,2-diphenylcyclopropanecarbaldehyde 
• 37555-48-9 2,2-diphenylcyclopropylmethanol 
• 67428-04-0 ethyl 2,2-diphenylcyclopropane-1-carboxylate 
• 530-48-3 1,1-Diphenylethylene 
• 32657-89-9 1,3-butadien-2-ylmagnesium chloride 
• 93319-68-7 1,1'-(2-ethynylcyclopropane-1,1-diyl)dibenzene 

Relevant academic research and scientific papers

Palladium-Catalyzed Stereoselective Cyclization of in Situ Formed Allenyl Hemiacetals: Synthesis of Rosuvastatin and Pitavastatin

A diastereoselective palladium-catalyzed cyclization of allenyl hemiacetals is described. It permits the selective synthesis of 1,3-dioxane derivatives, precursors for syn-configured 1,3-diols which make an appearance in all of the statin representatives. The reaction allows the total synthesis of Rosuvastatin and Pitavastatin in a straightforward fashion.

Aryl-substituted cyclopropyl acetylenes as sensitive mechanistic probes in the gold-catalyzed hydration of alkynes. comparison to the Ag(I)-, Hg(II)-, and Fe(III)-catalyzed processes

The gold-catalyzed hydration of 2-phenyl- or 2,2-diphenylcyclopropyl acetylene, sensitive probes to trace the formation of vinyl carbocations, provides exclusively the corresponding cyclopropyl methyl ketones. On the other hand, in the Ag(I)- or Fe(III)-c

Palladium-catalyzed 1-methylene-2-propenylation reactions of aryl bromides with 3,4-alkadien-1-ols via carbon-carbon bond cleavage for the synthesis of 2-aryl-1,3-butadiene derivatives

A method for the synthesis of 2-aryl-1,3-alkadienes has been developed. Treatment of aryl bromides with 3,4-alkadien-1-ols in the presence of a palladium catalyst results in 1-methylene-2-propenyl group transfer to aryl bromides. Taking advantage of palla

A Convenient Route to 2-Lithio-1,3-butadiene from Chloroprene via 2-Stannyl-1,3-butadiene

A convenient route to 2-lithio-1,3-butadiene from chloroprene via a 2-stannyl-1,3-butadiene is presented, and the regioselective additions to a variety of carbonyl groups are demonstrated.