612069-25-7

Basic information

• Product Name: 3'-Des(diMethylaMino)-3'-keto AzithroMycin
• Synonyms: 3'-Des(diMethylaMino)-3'-keto AzithroMycin;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[[4,6-dideoxy-β-D-erythro-hexopyranos-3-ulos-1-yl]oxy]-13-[(2,6-dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptaMe;Azithromycin EP Impurity N;Azithromycin Impurity N(BP)
• CAS NO: 612069-25-7
• Molecular Formula: C36H65NO13
• Molecular Weight: 719.9002
• Product Categories: Chiral Reagents;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 612069-25-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 823.2±65.0 °C(Predicted)
• Appearance: /
• Density: 1.21±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 11.58±0.60(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: 3'-Des(diMethylaMino)-3'-keto AzithroMycin(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-Des(diMethylaMino)-3'-keto AzithroMycin(612069-25-7)
• EPA Substance Registry System: 3'-Des(diMethylaMino)-3'-keto AzithroMycin(612069-25-7)

Safety Data

• Hazardous Substances Data: 612069-25-7(Hazardous Substances Data)

Usage

Uses

Azithromycin (A927000) impurity. A degradation products of Azithromycin.

Upstream product

• 83905-01-5 Zithromax(R) 
• 612069-27-9 3'-N,N-didemethyl-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A 

Relevant articles and documents

PROCESS FOR THE PURIFICATION OF AZITHROMYCIN BY SEPARATION FROM ITS THERMAL DEGRADATION PRODUCTS AND/OR ISOMERS

The present invention relates to methods for improving the purity of azithromycin, preferably by purifying azithromycin from degradation products and/or isomers. The invention describes a degradation product of azithromycin which may be produced during drying and/or storage of azithromycin and relates to methods of removing the degradation product(s). The invention further relates to a method for preparing azithromycin dihydrate from crude azithromycin containing the isomer azithromycin B. The invention furthermore relates to a combined process for making azithromycin dihydrate which combines the method for the purification of azithromycin from degradation products with the method for making azithromycin dihydrate which removes the isomer azithromycin B.