612071-89-3

Upstream product

• 3173-56-6 benzyl isothiocyanate 
• 611183-00-7 (+)-3-benzyl-4-hydroxy-hexahydrocyclopenta[d]oxazol-2-one 
• 34310-95-7 trans-6-oxabicyclo<3.1.0>hexan-2-ol 
• 68845-73-8 tert-butyl(cyclopent-2-en-1-yloxy)dimethylsilane 

Downstream Products

• 611183-01-8 N-(2,5-dihydroxycyclopentyl)-2-(thymin-1-yl)acetamide 
• 673458-62-3 N-(2,5-dihydroxycyclopentyl)-2-(N⁶-(p-methoxybenzoyl)adenin-1-yl)acetamide 
• 673458-63-4 N-[2-(tert-butyl(dimethyl)silyloxy)-5-(9-phenylxanthen-9-yloxy)cyclopentyl]-2-(thymin-1-yl)acetamide 
• 673458-64-5 N-[2-(tert-butyl(dimethyl)silyloxy)-5-(9-phenylxanten-9-yloxy)cyclopentyl]-2-(N⁶-(p-methoxybenzoyl)adenin-1-yl)acetamide 
• 673458-65-6 N-[2-hydroxy-5-(9-phenyl-9H-xanthen-9-yloxy)-cyclopentyl]-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetamide 
• 673458-66-7 N-(9-{[2-hydroxy-5-(9-phenyl-9H-xanthen-9-yloxy)-cyclopentylcarbamoyl]-methyl}-9H-purin-6-yl)-4-methoxy-benzamide 
• 611183-07-4 (2-cyanoethyl)[1'-(2-(thymin-1-yl)acetylamino)-3'-(9-phenylxanthen-9-yloxy)cyclopent-2'-yl]-N,N-diisopropylphosphoramidite 
• 611183-03-0 N-[2-(tert-butyl(dimethyl)silyloxy)-5-(9-phenylxanthen-9-yloxy)cyclopentyl]-2-(thymin-1-yl)acetamide 
• 611183-05-2 N-[2-hydroxy-5-(9-phenylxanthen-9-yloxy)cyclopentyl]-2-(thymin-1-yl)acetamide 

Relevant academic research and scientific papers

Synthesis of cyclopentane amide DNA (cpa-DNA) and its pairing properties

We recently reported on the synthesis and pairing properties of the DNA analogue bicyclo[3.2.1]-amide DNA (bca-DNA). In this analogue the nucleobases are attached via a linear, 4-bond amide-linker to a structurally preorganized sugar-phosphate backbone un

Synthesis of a cyclopentane amide DNA analogue and its base pairing properties

cpa-DNA monomers containing the bases adenine and thymine have been synthesized starting from the known compound 1 in 12 steps. Partially and fully modified cpa-thymidine and cpa-adenosine containing oligodeoxynucleotides were synthesized by standard olig