61212-23-5Relevant academic research and scientific papers
Rhodium(II)-catalyzed cross-coupling of diazo compounds
Hansen, Joorn H.,Parr, Brendan T.,Pelphrey, Philip,Jin, Quihui,Autschbach, Jochen,Davies, Huw M. L.
supporting information; experimental part, p. 2544 - 2548 (2011/04/27)
Nothing left to chance: A convenient protocol for selective cross-coupling of diazo compounds for the convergent synthesis of alkenes was developed (see scheme; EDG=aryl, heteroaryl, vinyl; R=O-alkyl, aryl). The selectivity control elements were identifie
Stereoselective preparation of highly functionalized (Z)-3-magnesiated enoates by an iodine - Magnesium exchange reaction
Sapountzis,Dohle,Knochel
, p. 2068 - 2069 (2007/10/03)
3-Iodoenoates are converted into the corresponding alkenylmagnesium species with complete retention of configuration of the double bond; both direct reaction and copper(I)-mediated reactions with various electrophiles provide polyfunctional enoates.
3α-Arylhydroisoindoles
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, (2008/06/13)
Certain 3α-arylhydroisoindoles are useful as analgesics and/or narcotic antagonists. Exemplary is N-cyclopropylmethyl-3α-(m-methoxyphenyl)-5,6-dimethyl-2,3,3α,4,7,7α-trans-hexahydroisoindole.
