61228-29-3Relevant academic research and scientific papers
On the Oxidation of Hydroxylamines with o -Iodoxybenzoic Acid (IBX)
Parmeggiani, Camilla,Matassini, Camilla,Cardona, Francesca,Goti, Andrea
, p. 2890 - 2900 (2017)
o -Iodoxybenzoic acid (IBX) is confirmed as a powerful tool for the oxidation of hydroxylamines. The synthetic route is demonstrated as efficient and user friendly, and is exploited on various carbohydrate-derived N,N-disubstituted hydroxylamines (cyclic, acyclic, and functionalized ones), affording the corresponding nitrones in good yields and regioselectivity. N-Monosubstituted hydroxylamines revealed an interesting divergent behavior depending on the reaction conditions. While IBX oxidation in dimethyl sulfoxide at 45 °C furnished oximes as reported, the oxidation in dichloromethane at room temperature afforded efficiently the unusual corresponding nitroso dimers.
RuO4-mediated oxidation of secondary amines. Part 1. Are hydroxylamines the main intermediates?
Florea, Cristina A.,Petride, Horia
, p. 475 - 486 (2016/07/20)
The RuO4-catalyzed oxidation of secondary amines Bn-NH-CH2R (1a and b; R=H, Me) gave mainly amides, but minute amounts of nitrones PhCH=N(O)-CH2R (9a and b) and traces of Bn-N(OH)-CH2R (R=H, 4a) were also detect
Selective N-oxidation of aromatic amines to nitroso derivatives using a molybdenum acetylide oxo-peroxo complex as catalyst
Biradar, Ankush V.,Kotbagi, Trupti V.,Dongare, Mohan K.,Umbarkar, Shubhangi B.
, p. 3616 - 3619 (2008/09/19)
The molybdenum acetylide oxo-peroxo complex obtained in situ by the treatment of the corresponding molybdenum acetylide carbonyl complex, CpMo(CO)3(C{triple bond, long}CPh); Cp = η5-C5H5 with H2O2, has been used as an efficient catalyst for selective N-oxidation of primary amines to nitroso derivatives. Excellent amine conversion (up to 100%) and very high selectivity for nitroso compounds (99%) have been obtained using 30% hydrogen peroxide as an oxidant. The oxo peroxo Mo(VI) complex has also been found to be very active for the oxidation of various substituted primary aromatic amines with electron donating as well as electron withdrawing substituents on the aromatic ring.
Studies on Annelated Pyrimidines: Reaction of 6-Hydroxylamino-1,3-dimethylpyrimidine-2,4-dione with Aldonitrones
Prajapati, Dipak,Sandhu, J. S.
, p. 758 (2007/10/02)
Reaction of 6-hydroxylamino-1,3-dimethylpyrimidine-2,4-dione (I) with aldonitrones (II) affords isoxazolopyrimidines in good yields.
Investigations on the Aprotic Deamination of Benzylamine and (α,α-2H2)Benzylamine
Bakke, Ian M.,Svendsen, K.
, p. 179 - 184 (2007/10/02)
The reaction of benzylamine with nitrosyl chloride in diethyl ether at -50 deg C gave diazotoluene (16percent), benzyl alcohol (15percent), benzyl chloride (31percent) and α,α-azoxytoluene (12percent) together with several other products.The same reaction
