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(S)-1-[(R)-2-METHOXY-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHYL]-2-METHYL-PIPERAZINE is a chemical compound with a molecular formula C18H26F3N3O. It is a piperazine derivative featuring a substituted phenyl group, a methoxy group, and a trifluoromethyl group. (S)-1-[(R)-2-METHOXY-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHYL]-2-METHYL-PIPERAZINE has potential pharmaceutical applications, particularly as a potential ligand for targeting dopamine receptors. Its structure suggests that it may have psychoactive or neurological effects, making it a promising candidate for further research and development in the field of medicinal chemistry.

612494-07-2

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612494-07-2 Usage

Uses

Used in Pharmaceutical Industry:
(S)-1-[(R)-2-METHOXY-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHYL]-2-METHYL-PIPERAZINE is used as a potential ligand for targeting dopamine receptors due to its unique structure and potential psychoactive or neurological effects. This makes it a promising candidate for the development of new medications in the field of medicinal chemistry, particularly for conditions related to dopamine receptor activity.

Check Digit Verification of cas no

The CAS Registry Mumber 612494-07-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,2,4,9 and 4 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 612494-07:
(8*6)+(7*1)+(6*2)+(5*4)+(4*9)+(3*4)+(2*0)+(1*7)=142
142 % 10 = 2
So 612494-07-2 is a valid CAS Registry Number.
InChI:InChI=1S/C15H21F3N2O/c1-11-9-19-7-8-20(11)14(10-21-2)12-3-5-13(6-4-12)15(16,17)18/h3-6,11,14,19H,7-10H2,1-2H3/t11-,14-/m0/s1

612494-07-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-1-[(R)-2-METHOXY-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHYL]-2-METHYL-PIPERAZINE

1.2 Other means of identification

Product number -
Other names (S)-1-((R)-2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-2-methylpiperazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:612494-07-2 SDS

612494-07-2Relevant academic research and scientific papers

Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists

Lemoine, Rémy C.,Petersen, Ann C.,Setti, Lina,Chen, Lijing,Wanner, Jutta,Jekle, Andreas,Heilek, Gabrielle,deRosier, André,Ji, Changhua,Rotstein, David M.

scheme or table, p. 1830 - 1833 (2010/07/02)

The bicyclic 5-amino-3-azabicyclo[3.3.0]octanes were shown to be effective replacements for the conformationally restricted 4-aminopiperidine ring found in several series of CCR5 antagonists.

Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. IV. Discovery of 1-[(4,6-Dimethyl-5-pyrimidinyl) carbonyl]-4-[4-{2-methoxy-1(R)-4-(trifluoromethyl)-phenyl}ethyl-3(S) -methyl-1-piperazinyl]-4-methylpiperidine (Sch-417690/Sch-D), a Potent, Highly Sel

Tagat, Jayaram R.,McCombie, Stuart W.,Nazareno, Dennis,Labroli, Marc A.,Xiao, Yushi,Steensma, Ruo W.,Strizki, Julie M.,Baroudy, Bahige M.,Cox, Kathleen,Lachowicz, Jean,Varty, Geoffrey,Watkins, Robert

, p. 2405 - 2408 (2007/10/03)

The nature and the size of the benzylic substituent are shown to be the key to controlling receptor selectivity (CCR5 vs M1, M2) and potency in the title compounds. Optimization of the lead benzylic methyl compound 3 led to the methoxymethyl analogue 30,

Stereoselective alkylation of chiral 2-methyl-4-protected piperazines

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Page/Page column 11, (2008/06/13)

In an illustrative embodiment, the present invention describes the synthesis of the following compound and similar compounds, in high stereochemical purity by a novel stereoselective alkylation process: 1

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