61251-97-6 Usage
Enzyme inhibitor
This anti-leukemia agent (FW = 562.61 g/mol; CAS 61251-97-6), also named (2'S,3'R,4'S, 7'R,9R,10S)-7'-deoxo-2'-deoxy-2',3':9,10-bisoxy-9,10- dihydro-4'-hydroxy-7'-[(R)-1-hydroxyethyl]verrucarin A, from the toxic South American plant known as green propolis (Baccharis megapotamica), is a likely mycotoxin that was later modified by Baccharis megapotamica. Baccharin is also a potent competitive inhibitor (Ki = 56 nM) of human aldo-keto reductase (AKR) 1C3, also known as 17β-hydroxysteroid dehydrogenase (Type 5) and prostaglandin F synthase. AKR is regarded as a druggable target in the treatment of prostate and breast cancers. Baccharin shows no significant inhibition toward the AKR1C1, AKR1C2, and AKR1C4 isoforms. Moreover, non-prenyl analogues of baccharin as selective and potent inhibitors for AKR1C3.
Check Digit Verification of cas no
The CAS Registry Mumber 61251-97-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,2,5 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 61251-97:
(7*6)+(6*1)+(5*2)+(4*5)+(3*1)+(2*9)+(1*7)=106
106 % 10 = 6
So 61251-97-6 is a valid CAS Registry Number.
