612548-92-2

Upstream product

• 1458-98-6 2-methyl-3-bromo-1-propene 
• 1997-85-9 N-(2,2,2-trifluoroethylidene)benzylamine 
• 106-95-6 allyl bromide 
• 592537-90-1 N-benzyl-1,1,1-trifluoro-4-methyl-4-penten-2-amine 

Relevant academic research and scientific papers

Aminated compounds bearing at least an allyl and a difluoromethyl and method used for synthesis thereof

The invention relates to aminated compounds bearing at least an allyl and a difluoromethyl and a method used for synthesis thereof. Said compounds comprise at least one carbon bearing: an amine function, an allyl or propargyl radical, a difluoromethylene

A one-pot synthesis of doubly unsaturated trifluoromethyl amines: Easy access to CF3-substituted piperidines

A straightforward route to trifluoromethyl analogs of piperidines is described. These syntheses involve a Barbier-type allylation reaction of trifluoroacetaldimines, followed by N-allylation (one-pot), and ring-closing metathesis. An efficient asymmetric