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1H-Pyrazole, 3-methyl-1-[(4-methylphenyl)sulfonyl]-, also known as 3-Methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrazole, is a chemical compound with the molecular formula C11H12N2O2S. It is a derivative of pyrazole, a five-membered heterocyclic aromatic organic compound containing one nitrogen atom and two carbon atoms. The compound features a methyl group at the 3-position of the pyrazole ring and a sulfonyl group attached to the 1-position, which is derived from 4-methylphenyl. This specific chemical structure may have potential applications in various fields, such as pharmaceuticals, agrochemicals, or materials science, due to its unique properties and reactivity.

6126-11-0

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6126-11-0 Usage

Structure

Pyrazole derivative with a methyl group at the 3-position and a sulfonyl group attached to the 1-position of the pyrazole ring

Usage

Building block in organic synthesis and pharmaceutical research

Properties

Potential pharmacological properties, studied for potential use in drug development

Importance

Unique structure and properties make it an important compound in medicinal chemistry and drug discovery.

Check Digit Verification of cas no

The CAS Registry Mumber 6126-11-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,2 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6126-11:
(6*6)+(5*1)+(4*2)+(3*6)+(2*1)+(1*1)=70
70 % 10 = 0
So 6126-11-0 is a valid CAS Registry Number.

6126-11-0Downstream Products

6126-11-0Relevant academic research and scientific papers

Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: An efficient strategy for the synthesis of substituted 1-tosyl-1: H -pyrazoles

Zhang, Bang-Hong,Lei, Lin-Sheng,Liu, Si-Zhan,Mou, Xue-Qing,Liu, Wei-Ting,Wang, Shao-Hua,Wang, Jie,Bao, Wen,Zhang, Kun

supporting information, p. 8545 - 8548 (2017/08/04)

A Zn(OTf)2-promoted cyclization reaction of tosylhydrazones with 2-(dimethylamino)malononitrile has been successfully developed providing an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles.

Base-promoted ecofriendly synthesis of trisubstituted pyrazoles from α,β-alkynyl N-tosylhydrazones under metal- and solvent-free conditions

Li, Ning,Li, Baoguo,Chen, Shufeng

supporting information, p. 1597 - 1601 (2016/06/14)

A simple and green method is described for the synthesis of trisubstituted pyrazoles from α,β-alkynyl N-tosylhydrazones under metal- and solvent-free conditions. Notably, only diisopropylamine is required as a promoter, and the reaction can be easily perf

A new synthesis of pyrazoles through a Lewis acid catalyzed union of 3-ethoxycyclobutanones with monosubstituted hydrazines

Shan, Gang,Liu, Pengfei,Rao, Yu

supporting information; experimental part, p. 1746 - 1749 (2011/05/12)

A new efficient and convenient approach toward the synthesis of pyrazoles is described. Through a Lewis acid catalyzed union of 3-ethoxycyclobutanones with monosubstituted hydrazines, a variety of pyrazole derivatives were prepared readily at ambient temp

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