6126-53-0

Basic information

• Product Name: 2-(2-Oxopropyl)cyclohexan-1-one
• Synonyms: 2-(2-Oxopropyl)cyclohexan-1-one;2-Acetonyl-1-cyclohexanone;2-(2-Oxo-propyl)-cyclohexanone
• CAS NO: 6126-53-0
• Molecular Formula: C₉H₁₄O₂
• Molecular Weight: 154.21
• Mol File: 6126-53-0.mol
• Article Data: 43

Chemical Properties

• Melting Point: 203-205 °C
• Boiling Point: 91-93 °C(Press: 1.1 Torr)
• Appearance: /
• Density: 1.0235 g/cm3
• CAS DataBase Reference: 2-(2-Oxopropyl)cyclohexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Oxopropyl)cyclohexan-1-one(6126-53-0)
• EPA Substance Registry System: 2-(2-Oxopropyl)cyclohexan-1-one(6126-53-0)

Safety Data

• Hazardous Substances Data: 6126-53-0(Hazardous Substances Data)

Usage

Compound type

Cyclic ketone

Substituent group

2-Oxopropyl group attached to the cyclohexane ring

Uses

Production of fragrances and flavors, synthesis of pharmaceuticals and other organic compounds

Odor

Characteristic sweet and fruity

Applications

Flavoring agent in food products and beverages, potential use in drug development due to versatile chemical properties.

Upstream product

• 26562-24-3 3-bromo-2-methoxypropene 
• 10468-40-3 cyclohexanone N-cyclohexylimine 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 6704-27-4 (acetylmethyl)mercury chloride 
• 4749-28-4 2-nitropropene 
• 108-94-1 cyclohexanone 
• 108-22-5 Isopropenyl acetate 
• 65700-06-3 percarbonate de O,O-tert-butyle et O-isopropyle 
• 930-68-7 cyclohexenone 
• 598-31-2 1-bromoacetone 
• 13332-18-8 1-(bicyclo[4.1.0]heptan-7-yl)ethan-1-one 
• 17851-97-7 1-tri(n-butyl)stannyloxy-1-cyclohexene 
• 78-95-5 chloroacetone 
• 936-67-4 2-(2-methyl-2-propenyl)cyclohexanone 

Downstream Products

• 95-20-5 2-methyl-1H-indole 
• 1195-14-8 2-Methylbenzothiophene 
• 13351-29-6 cis-2H-1,3,3a,4,5,6,7,7a-octahydro-7a-methyl-2-indenone 
• 90642-57-2 2-methyl-4,5,6,7-tetrahydro-1H-indole 

Relevant articles and documents

Synthesis of Substituted Anilines from Cyclohexanones Using Pd/C-Ethylene System and Its Application to Indole Synthesis

The synthesis of anilines and indoles from cyclohexanones using a Pd/C-ethylene system is reported. A simple combination of NH4OAc and K2CO3 under nonaerobic conditions was found to be the most suitable to perform this reaction. Hydrogen transfer between cyclohexanone and ethylene generates the desired products. The reaction tolerates a variety of substitutions on the starting cyclohexanones.

Intramolecular Schmidt Reaction of Vinyl Azides with Cyclic Ketones

Cyclic ketones tethered with a vinyl azide group undergo a Schmidt-hydrolysis sequence to give secondary lactams bearing a ketone side chain. Secondary lactams are obtained in a regioselective manner that is not possible in a conventional Schimdt reaction. In addition to the well-documented C-2 nucleophilicity, the N nucleophilicity of vinyl azide disclosed in this work opens a new direction for reaction invention involving vinyl azides.

CANNABINOID AGONISTS

The present disclosure relates to compounds useful as agonists of the cannabinoid receptors. The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment of various disorders, either alone or in combination therapy. The compounds of the invention have Formula (I).