6126-55-2Relevant articles and documents
Synthesis and conformational analysis of macrocyclic dilactones mimicking the pharmacophore of aplysiatoxin
Knust, Henner,Hoffmann, Reinhard W.
, p. 1871 - 1893 (2007/10/03)
A small number of macrocyclic dilactones of type 3, i.e., 9, 10, 11, and epi-11, comprising a 3,4-dihydroxypentanoic acid unit, the pharmacophore of aplysiatoxin, and a conformationally preorganized ω-hydroxynonanoic acid unit were synthesized. Conformati