6127-75-9 Usage
Description
(3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-17-[(2R)-6,7-dihydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is a complex steroid molecule with a cyclopenta[a]phenanthrene core structure. It contains multiple hydroxyl groups and is derived from cholesterol. This molecule is a precursor to various hormones and has important biological functions in the body, including regulating metabolism, inflammation, and immune response. Its specific stereochemistry and functional groups make it a critical component in the body's endocrine system and a target for pharmaceutical research and development.
Uses
Used in Pharmaceutical Industry:
(3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-17-[(2R)-6,7-dihydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is used as a precursor for the synthesis of various hormones for the treatment of hormonal imbalances and related disorders.
Used in Research and Development:
(3R,5S,7R,8S,9S,10S,12S,13R,14S,17R)-17-[(2R)-6,7-dihydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is used as a target for pharmaceutical research and development to discover new drugs and therapies for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 6127-75-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,2 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6127-75:
(6*6)+(5*1)+(4*2)+(3*7)+(2*7)+(1*5)=89
89 % 10 = 9
So 6127-75-9 is a valid CAS Registry Number.
InChI:InChI=1/C27H48O5/c1-16(6-5-10-25(2,32)15-28)19-7-8-20-24-21(14-23(31)27(19,20)4)26(3)11-9-18(29)12-17(26)13-22(24)30/h16-24,28-32H,5-15H2,1-4H3/t16-,17+,18-,19-,20+,21+,22-,23+,24+,25?,26+,27-/m1/s1
6127-75-9Relevant articles and documents
IDENTIFICATION OF 5β-CHOLESTANE-3α,7α,12α,25,26-PENTOL IN CEREBROTENDINOUS XANTHOMATOSIS
Dayal, B.,Tint, G. S.,Greeley, D. N.,Williams, T. H.,Salen, G.
, p. 441 - 448 (2007/10/02)
An unrecognized pentahydroxy bile alcohol has been isolated from the bile and feces of patients with cerebrotendinous xanthomatosis (CTX).Its structure, 5β-cholestane-3α,7α,12α,25,26-pentol has been deduced by spectroscopic methods and confirmed by comparison with a synthetic analog.
