61272-72-8 Usage
Uses
Used in Pharmaceutical Industry:
5-fluoro-1H-indazol-3-amine is used as a synthetic intermediate for the development of novel pharmaceutical compounds. Its unique structure, including the fluorine atom, can enhance the pharmacokinetic and pharmacodynamic properties of the resulting drugs, potentially leading to improved efficacy and safety profiles.
Used in Agrochemical Industry:
5-fluoro-1H-indazol-3-amine is employed as a building block in the synthesis of agrochemicals, such as pesticides and herbicides. The presence of the fluorine atom can contribute to the compound's stability and activity, making it a valuable component in the development of effective and environmentally friendly agrochemical products.
Used in Medicinal Chemistry Research:
5-fluoro-1H-indazol-3-amine serves as a key component in medicinal chemistry research, where it is used to explore the structure-activity relationships of various biologically active molecules. Its unique structural features can provide insights into the design of new drugs with improved potency, selectivity, and reduced side effects.
Used in Drug Discovery:
5-fluoro-1H-indazol-3-amine is utilized in drug discovery processes to identify and optimize potential drug candidates. Its presence in compound libraries can facilitate the screening and selection of molecules with desirable biological activities, accelerating the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 61272-72-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,2,7 and 2 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 61272-72:
(7*6)+(6*1)+(5*2)+(4*7)+(3*2)+(2*7)+(1*2)=108
108 % 10 = 8
So 61272-72-8 is a valid CAS Registry Number.
61272-72-8Relevant academic research and scientific papers
Two-step synthesis of substituted 3-aminoindazoles from 2-bromobenzonitriles
Lefebvre, Valerie,Cailly, Thomas,Fabis, Frederic,Rault, Sylvain
supporting information; experimental part, p. 2730 - 2732 (2010/07/08)
A general two-step synthesis of substituted 3-aminoindazoles from 2-bromobenzonitriles involving a palladium-catalyzed arylation of benzophenone hydrazone followed by an acidic deprotection/cyclization sequence is described. This procedure offers a general and efficient alternative to the typical S NAr reaction of hydrazine with o-fluorobenzonitriles.
INDAZOLE DERIVATIVES
-
Page/Page column 14, (2008/06/13)
The invention is concerned with novel indazole derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6, X and Y are as defined in the description and in the claims, as well as physiologic
3-Aminoindazole derivatives
-
, (2008/06/13)
.Iadd.Pharmaceutical compositions having muscle relaxant and analgesic activity containing 3-aminoindazoles..Iaddend.
