61278-30-6 Usage
Description
D-SACCHARIC ACID 1 4-LACTONE, also known as D-SACCHARIC ACID 1 4-LACTONE monohydrate (DSAL), is a white solid with the ability to inhibit the activity of β-glucuronidase enzyme. It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).
Uses
Used in Enzyme Activity Assays:
D-SACCHARIC ACID 1 4-LACTONE is used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. This application is crucial for accurately measuring the enzyme's activity without interference from β-glucuronidase.
Used in Iduronidase Activity Assay:
D-SACCHARIC ACID 1 4-LACTONE is used as a component of the reaction mixture in Iduronidase activity assay. Iduronidase is an enzyme involved in the breakdown of glycosaminoglycans, and its activity is essential for diagnosing and monitoring certain lysosomal storage diseases.
Used in UDP-glucuronosyltransferase 1 (UGT1A1) Inhibition Assay:
D-SACCHARIC ACID 1 4-LACTONE is used as a component in the inhibition assay of UDP-glucuronosyltransferase 1 (UGT1A1), an enzyme that plays a vital role in the metabolism and detoxification of various endogenous and exogenous compounds, including drugs and toxins.
Check Digit Verification of cas no
The CAS Registry Mumber 61278-30-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,2,7 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 61278-30:
(7*6)+(6*1)+(5*2)+(4*7)+(3*8)+(2*3)+(1*0)=116
116 % 10 = 6
So 61278-30-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1?,2-,3+,4+;/m1./s1
