612843-21-7

Basic information

• Product Name: 1,2-bis-(diphenylphosphinoyl)-hexan-3-one
• Synonyms: 1,2-bis-(diphenylphosphinoyl)-hexan-3-one
• CAS NO: 612843-21-7
• Molecular Weight: 500.514
• Mol File: 612843-21-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-bis-(diphenylphosphinoyl)-hexan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis-(diphenylphosphinoyl)-hexan-3-one(612843-21-7)
• EPA Substance Registry System: 1,2-bis-(diphenylphosphinoyl)-hexan-3-one(612843-21-7)

Safety Data

• Hazardous Substances Data: 612843-21-7(Hazardous Substances Data)

Upstream product

• 105-54-4 butanoic acid ethyl ester 
• 984-43-0 1,2-bis(diphenylphosphanyl)ethane monoxide 

Relevant articles and documents

Synthesis of allyl phosphine oxides/boranes via Horner reaction of bis(diphenylphosphine)ethane monoxide reagent with an aldehyde

The Horner-Wittig addition-elimination reaction using bis(diphenylphosphine)ethane monoxide [DIPHOS(O)] with an aldehyde affords Z-allyl phosphine oxides/boranes. Alternatively, the stereoselective Lewis acid mediated intermolecular reduction of its γ-ketobisphosphoranes and stereoselective intramolecular reduction of γ-ketophosphine·borane derivatives followed by elimination of diphenylphosphinate affords E-allyl phosphine oxides/boranes with good to high selectivity. Allyl phosphine oxides are common intermediates in the synthesis of polyenes.