612844-82-3

Upstream product

• 327-78-6 4-chloro-3-(trifluoromethyl)phenyl isocyanate 
• 454-92-2 3-(trifluoromethyl)benzoic acid 
• 612844-78-7 phenyl 2-O-(2-amino-2-deoxy-β-D-glucopyranosyl)-3-azido-3-deoxy-4-O-methyl-1-thio-β-D-glucopyranosiduronamide 
• 499115-49-0 2-chloroethyl 2-O-(2-deoxy-3,4,6-tri-O-acetyl-2-[3-(trifluoromethyl)benzamido]-β-D-glucopyranosyl)-3-azido-3-deoxy-4-O-methyl-β-D-glucopyranosiduronamide 
• 302352-19-8 phenyl 2-O-(2-deoxy-2-phthalimido-3,4,6-tri-O-acetyl-β-D-glucopyranosyl)-3-azido-3-deoxy-4-O-methyl-1-thio-β-D-glucopyranosiduronamide 
• 612844-79-8 phenyl 2-O-(2-deoxy-2-[3-(trifluoromethyl)benzamido]-β-D-glucopyranosyl)-3-azido-3-deoxy-4-O-methyl-1-thio-β-D-glucopyranosiduronamide 
• 394247-91-7 phenyl 2-O-(2-deoxy-3,4,6-tri-O-acetyl-2-[3-(trifluoromethyl)benzamido]-β-D-glucopyranosyl)-3-azido-3-deoxy-4-O-methyl-1-thio-β-D-glucopyranosiduronamide 

Downstream Products

• 499115-50-3 2-iodoethyl 2-O-(2-deoxy-2-[3-(trifluoromethyl)benzamido]-β-D-glucopyranosyl)-3-[3-[4-chloro-3-(trifluoromethyl)phenyl]ureido]-3-deoxy-4-O-methyl-β-D-glucopyranosiduronamide 

Relevant academic research and scientific papers

Structural requirements for vanA activity of vancomycin analogues

We have prepared several sets of glycopeptide analogues in order to probe the molecular basis for the activity of derivatives that overcome vanA resistance. The results described in this paper provide compelling evidence that good vanA activity is due to