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WUWEIZISU C, also known as Schisandrin C, is a lignan originally isolated from Schizandrae that exhibits a wide range of biological activities. It has the ability to decrease the viability of U937 cells in a concentration-dependent manner and induce cell cycle arrest at the G1 phase. Additionally, it demonstrates protective effects against hydrogen peroxide-induced cell death and the production of reactive oxygen species (ROS) in C2C12 skeletal muscle cells. WUWEIZISU C also reduces the levels of various inflammatory markers and enzymes in hydrogen peroxide-stimulated C2C12 cells and decreases the production of nitric oxide and other inflammatory mediators in mouse primary microglia. In vivo, it has been shown to decrease serum alanine amino transferase (ALT) and aspartate amino transferase (AST) activity, increase hepatic mitochondrial and total glutathione (GSH) levels, and reduce liver injury in a mouse model of acetaminophen-induced liver injury.

61301-33-5

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61301-33-5 Usage

Uses

Used in Pharmaceutical Industry:
WUWEIZISU C is used as a therapeutic agent for its diverse biological activities, including its ability to decrease cell viability, induce cell cycle arrest, protect against hydrogen peroxide-induced cell death, and reduce the production of inflammatory markers and enzymes.
Used in Neuroprotection:
WUWEIZISU C is used as a neuroprotective agent for its strong protective effects in SH-SY5Y cells against serum and glucose deprivation (SGD) injury.
Used in Liver Protection:
WUWEIZISU C is used as a hepatoprotective agent for its ability to decrease serum ALT and AST activity, increase hepatic mitochondrial and total GSH levels, and reduce liver injury in a mouse model of acetaminophen-induced liver injury.
Used in Inflammation and Immune Modulation:
WUWEIZISU C is used as an anti-inflammatory and immune modulatory agent for its ability to decrease the production of nitric oxide and other inflammatory mediators in mouse primary microglia, as well as its potential to inhibit proprotein convertase subtislin-kexin type 9 (PCSK9) mRNA expression.

Check Digit Verification of cas no

The CAS Registry Mumber 61301-33-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,0 and 1 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 61301-33:
(7*6)+(6*1)+(5*3)+(4*0)+(3*1)+(2*3)+(1*3)=75
75 % 10 = 5
So 61301-33-5 is a valid CAS Registry Number.

61301-33-5 Well-known Company Product Price

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  • Sigma

  • (SMB00323)  Schisandrin C  ≥98% (HPLC)

  • 61301-33-5

  • SMB00323-5MG

  • 4,208.49CNY

  • Detail

  • Sigma

  • (SMB00323)  Schisandrin C  ≥98% (HPLC)

  • 61301-33-5

  • SMB00323-10MG

  • 7,979.40CNY

  • Detail

61301-33-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name WUWEIZISU C

1.2 Other means of identification

Product number -
Other names Schisandrin C

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61301-33-5 SDS

61301-33-5Downstream Products

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