61319-84-4

Basic information

• Product Name: 1-Cyclopentene-1-carboxylic acid, 2-(3-pyridinylamino)-, ethyl ester
• CAS NO: 61319-84-4
• Molecular Formula: C13H16N2O2
• Molecular Weight: 232.282
• Mol File: 61319-84-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Cyclopentene-1-carboxylic acid, 2-(3-pyridinylamino)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclopentene-1-carboxylic acid, 2-(3-pyridinylamino)-, ethyl ester(61319-84-4)
• EPA Substance Registry System: 1-Cyclopentene-1-carboxylic acid, 2-(3-pyridinylamino)-, ethyl ester(61319-84-4)

Safety Data

• Hazardous Substances Data: 61319-84-4(Hazardous Substances Data)

Upstream product

• 1462-86-8 3-amino-pyridine-2-carboxylic acid 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 

Relevant articles and documents

HAMMICK CYCLIZATIONS STUDIES ON THE MECHANISM OF THE HAMMICK REACTION

Heating of 3-hydroxypicolinic acid with the acetylketene precursor 2,2,4-trimethyldioxin-4-one, ethyl acetoacetate or ethyl 2-cyclopentaneonecarboxylate leads via the 3-O-acylated 3-hydroxypicolinic acids, which cannot be isolated, and subsequent decarboxylation to the corresponding Hammick cyclization products in up to 25 percent yields besides 3-hydroxypyridine.In the case of 3-aminopicolinic acid the 3-(3-oxobutyrylamido)picolinic acid can be isolated but gives on heating only 3-aminopyridine and 3-(3-oxobutyrylamido)pyridine albeit none of the anticipated Hammick cyclization products.The Hammick cyclization reactions, side reactions and reaction mechanisms are discussed.