613241-21-7

Upstream product

• 289900-59-0 1,3-dimethyl-5-(methylamino)pyrimidine-2,4(1H,3H)-dione 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 7033-39-8 5-bromo-1,3-dimethyluracil 

Relevant academic research and scientific papers

Palladium-catalyzed intramolecular arylation of pyrimidines: a novel and expedient avenue to benzannulated pyridopyrimidines

A new efficient protocol for the synthesis of benzannulated pyrido[2,3-d]- and pyrido[3,2-d]pyrimidines has been successfully accomplished via the palladium-catalyzed intramolecular arylation of C-H bond of pyrimidine moiety. The methodology has also been

C-C bond formation by radical cyclization: Synthesis of pyrimidine-annulated heterocycles

A number of pyrimidino[3,2-c]tetrahydroisoquinolin-2,4-diones are synthesized in excellent yields from 1,3-dialkyl-5-(N-2′-bromobenzyl,N-methyl)aminopyrimidine-2,4-diones by intramolecular addition of aryl radical to the uracil ring beating the amino nitrogen atom. Usual aerial oxidation in this type of cyclization with Bu3SnH is not observed in the present instance.