6133-18-2

Basic information

• Product Name: 2,2,7,8-Tetramethyl-6-hydroxychroman-5-carbaldehyde
• Synonyms: 2,2,7,8-Tetramethyl-6-hydroxychroman-5-carbaldehyde;3,4-Dihydro-6-hydroxy-2,2,7,8-tetramethyl-2H-1-benzopyran-5-carbaldehyde
• CAS NO: 6133-18-2
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 234.29
• Mol File: 6133-18-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2,7,8-Tetramethyl-6-hydroxychroman-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,7,8-Tetramethyl-6-hydroxychroman-5-carbaldehyde(6133-18-2)
• EPA Substance Registry System: 2,2,7,8-Tetramethyl-6-hydroxychroman-5-carbaldehyde(6133-18-2)

Safety Data

• Hazardous Substances Data: 6133-18-2(Hazardous Substances Data)

Usage

Uses

Used in Cosmetic and Personal Care Products:
2,2,7,8-Tetramethyl-6-hydroxychroman-5-carbaldehyde is used as an antioxidant for its ability to protect the skin from oxidative stress and environmental factors, thereby maintaining skin health and integrity.
Used in Skincare Formulations:
In the skincare industry, 2,2,7,8-Tetramethyl-6-hydroxychroman-5-carbaldehyde is used as an active ingredient in anti-aging and skin brightening products. Its antioxidant properties help in reducing the visible signs of aging and enhancing skin radiance.
Used in Antioxidant Formulations:
2,2,7,8-Tetramethyl-6-hydroxychroman-5-carbaldehyde is utilized in various formulations that aim to provide antioxidant support to the skin, combating the harmful effects of free radicals and contributing to overall skin wellness.

Upstream product

• 950-99-2 2,2,5,7,8-pentamethylchroman-6-ol 
• 64-17-5 ethanol 

Relevant articles and documents

Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

An α-tocopherol model compound, 2,2,5,7,8-pentamethyl-6-chromanol, reacted with nitric oxide (NO) in the presence of various amounts of oxygen to afford four major products. Distribution of the products was varied depending on the ratio of NO and O2

Oxidations of Vitamin E (α-Tocopherol) and Its Model Compound 2,2,5,7,8-Pentamethyl-6-hydroxychroman. A New Dimer

Oxidation of α-tocopherol (1a) with tert-butyl hydroperoxide in reagent-grade chloroform gave a new dimeric product which appeared to be both aromatic quinonoid.Repetition of the reaction with the tocopherol model compound 2,2,5,7,8-pentamethyl-6-hydroxychroman (1b) gave the corresponding dimer in high yield (30percent).This product was shown by two-dimensional, long-range proton-carbon correlation NMR spectra and subsequently by X-ray diffraction to be 2,3-dihydro-3,3,5,6,9,10,11a(R)-heptamethyl-7a(S)-(3-hydroxy-3-methylbutyl)-1H-pyranoxanthene-8(7aH),11(11aH)-dione (16b).It appeared to be formed by Diels-Alder addition of the intermediate quinone methide 7b to 2-(3-hydroxy-3-methylbutyl)-3,5,6-trimethylbenzo-1,4-quinone (14b), a known product of oxidation.