61345-87-7

Usage

Common uses

Crosslinking agent or curing agent in epoxy resins and adhesives, curing agent for epoxy coatings, hardening agent in the production of polyurethane foams

Reactivity

High degree of reactivity

Industrial applications

Production of coatings, sealants, and adhesives

Safety measures

Can cause skin and eye irritation, may be harmful if inhaled or ingested, proper safety measures should be taken when handling and using in industrial or laboratory settings.

Upstream product

• 61345-88-8 C₁₂H₂₂N₄ 
• 5460-29-7 2-(3-bromopropyl)isoindole-1,3-dione 
• 121259-53-8 N,N <(dimethyl-2,5 pyrolido)-3 propyl> N,N'dimethyl butane diamine 1,4 

Downstream Products

• 1262993-77-0 (2E,2'E)-N,N'-(3,3'-(butane-1,4-diylbis(methylazanediyl))bis(propane-3,1-diyl))bis(2-(benzyloxyimino)-3-(3,5-dibromo-4-methoxyphenyl)propanamide) 

Relevant academic research and scientific papers

A Cell-Permeable ATP Analogue for Kinase-Catalyzed Biotinylation

ATP analogues have been powerful compounds for the study of kinase-catalyzed phosphorylation. However, the cell impermeability of ATP analogues has largely limited their use to invitro lysate-based experiments. Herein, we report the first cell-permeable ATP analogue, ATP-polyamine-biotin (APB). APB is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. More generally, these studies provide a foundation for the development of additional cell-permeable ATP analogues for cell-signaling research. A cell-permeable ATP analogue, ATP-polyamine-biotin (APB), acts as a cosubstrate for kinase-catalyzed biotinylation incellulo. APB provides a foundation for the development of additional cell-permeable ATP analogues for cell-signaling research.

An improved total synthesis of spermatinamine, an inhibitor of isoprenylcysteine carboxy methyltransferase

An improved total synthesis of spermatinamine, an inhibitor of the anticancer target, isoprenylcysteine carboxy methyltransferase (Icmt) was accomplished from the commercially available 3,4-dibromo-4-hydroxybenzaldehyde via a high yielding reaction sequen

SYNTHESE DE SPERMINE ET DE SPERMIDINE SELECTIVEMENT SUBSTITUEES SUR LES FONCTIONS AMINES SECONDAIRES

Protection of the primary amino group of various polyamines followed by alkylation or benzoylation at the secondary amino group and finally removal of the protecting group leads to the N-methyl (23, Scheme 3), N-benzoyl (11, Scheme 1) (ethylenetriamine, N-benzoyl spermidine (22, Scheme 3), N,N'-methyl (27, Scheme 4)-ethyl (28, Scheme 4), -propyl (16, Scheme 2) -benzoyl (15, Scheme 2) spermine.