61350-61-6Relevant academic research and scientific papers
Isolation of pandamarilactonine-H from the roots of Pandanus amaryllifolius and synthesis of epi -pandamarilactonine-H
Tan, Mario A.,Kitajima, Mariko,Kogure, Noriyuki,Nonato, Maribel G.,Takayama, Hiromitsu
, p. 1453 - 1455 (2010)
A new alkaloid (1a), named pandamarilactonine-H, which possesses a methyl-2-(pyrrolidin-2-yl)acetate function, was isolated from the roots of Pandanus amaryllifolius. Eleven known alkaloids were also isolated. Unambiguous assignment of the structure of 1a, including the absolute configuration, was accomplished by spectroscopic analysis and total synthesis of its enantiomer.
BIPHENYL COMPOUNDS AND USES THEREOF
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, (2015/05/19)
The present invention relates to biphenyl compounds and uses thereof in medicine. Specifically, the present invention relates to a compound of Formula (I), or a stereoisomer, a geometric isomer, a tautomer, a mesomer, a racemate, an enantiomer, a diastereoisomer, an N-oxide, a hydrate, a solvate, a metabolite, a hydrolysate, a pharmaceutically acceptable salt or a prodrug thereof. The compound disclosed herein is used as a therapeutic agent particularly a GPR40 agonist for treating diabetes and metabolic disease in a patient.
